ArticleHuman brain mapping2017
The left dorsolateral prefrontal cortex and caudate pathway: New evidence for cue-induced craving of smokers.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Trial
- Closed-loop transcranial alternating current stimulation (tACS) reduces cue reactivity and improves inhibitory control in methamphetamine use disorder with frequency and timing specificity.Molecular psychiatry · 2026Article
- rTMS Suppresses Tobacco Craving via Enhanced Prefronto-Striato-Thalamic Connectivity.Addiction biology · 2026Article
- Article
- Association of Menstrual Cycle with Fronto-Striatal Connectivity and Delay Discounting.Behavioral sciences (Basel, Switzerland) · 2025Article
- Left Ventral Caudate Functional Connectivity Mediates the Relationship Between Habitual Responding and Alcohol Use.The European journal of neuroscience · 2025Article
- The effects of intermittent theta burst stimulation (iTBS) on resting-state brain entropy (BEN).Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Socioeconomic Status, Trauma, Cognitive Function, Impulsivity, Reward Salience, and Future Substance Use: Role of Left Caudate Connectivity with the Cingulo-Opercular Network.Journal of cellular neuroscience · 2025Article
- The Role of Social Media Use and Associated Risk and Protective Behaviors on Depression in Youth Adults: A Longitudinal and Network Perspective.International journal of mental health and addiction · 2024Article
- Dopamine and Norepinephrine Tissue Levels in the Developing Limbic Brain Are Impacted by the HumanInternational journal of molecular sciences · 2024Article
- Disentangling the neurobiological bases of temporal impulsivity in Huntington's disease.Brain and behavior · 2024Article
- Assessment of corticospinal tract damage and cytokines response in early and late stages of acute unilateral brainstem infarction patients.Frontiers in immunology · 2024Article
- A 3D pseudo-continuous arterial spin labeling study of altered cerebral blood flow correlation networks in mild cognitive impairment and Alzheimer's disease.Frontiers in aging neuroscience · 2024Article
- Implications of neuroimaging findings in addiction.Psychoradiology · 2023Review
- Neuroeconomic predictors of smoking cessation outcomes: A preliminary study of delay discounting in treatment-seeking adult smokers.Psychiatry research. Neuroimaging · 2022Article
- Partial recovery of the left DLPFC-right insula circuit with reduced craving in abstinent heroin users: a longitudinal study.Brain imaging and behavior · 2022Article
- Tract-specific white matter microstructural alterations in subjects with schizophrenia and unaffected first-degree relatives.Brain imaging and behavior · 2022Article
- Effects of acupuncture stimulation on brain activation induced by cue-elicited alcohol craving.Neural regeneration research · 2022Article
- Abnormal hippocampal substructure volume in insomnia disorder.Brain imaging and behavior · 2022Article
- Comparison of frontostriatal circuits in adolescent nicotine addiction and internet gaming disorder.Journal of behavioral addictions · 2022Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the activation of the prefrontal cortex (PFC) and the striatum had been found in smoking cue induced craving task, whether and how the functional interactions and white matter integrity between these brain regions contribute to craving processing during smoking cue exposure remains unknown. Twenty-five young male smokers and 26 age- and gender-matched nonsmokers participated in the smoking cue-reactivity task. Craving related brain activation was extracted and psychophysiological interactions (PPI) analysis was used to specify the PFC-efferent pathways contributed to smoking cue-induced craving. Diffusion tensor imaging (DTI) and probabilistic tractography was used to explore whether the fiber connectivity strength facilitated functional coupling of the circuit with the smoking cue-induced craving. The PPI analysis revealed the negative functional coupling of the left dorsolateral prefrontal cortex (DLPFC) and the caudate during smoking cue induced craving task, which positively correlated with the craving score. Neither significant activation nor functional connectivity in smoking cue exposure task was detected in nonsmokers. DTI analyses revealed that fiber tract integrity negatively correlated with functional coupling in the DLPFC-caudate pathway and activation of the caudate induced by smoking cue in smokers. Moreover, the relationship between the fiber connectivity integrity of the left DLPFC-caudate and smoking cue induced caudate activation can be fully mediated by functional coupling strength of this circuit in smokers. The present study highlighted the left DLPFC-caudate pathway in smoking cue-induced craving in smokers, which may reflect top-down prefrontal modulation of striatal reward processing in smoking cue induced craving processing. Hum Brain Mapp 38:4644-4656, 2017. © 2017 Wiley Periodicals, Inc.
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