ArticlePhysiological measurement2017
Continuous assessment of schizophrenia using heart rate and accelerometer data.
Article in Physiological measurement, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Wearable sensing for quantifying cognitive and balance functions in naturalistic movements of older adults with mild cognitive impairment in therapeutic environments.medRxiv : the preprint server for health sciences · 2026Article
- LINC: a framework for maintaining high-quality passive data in digital phenotyping studies.Scientific reports · 2026Article
- Deep learning approach for automatic assessment of schizophrenia and bipolar disorder in patients using R-R intervals.PLoS computational biology · 2025Article
- Neuro-Nutrition and Exercise Synergy: Exploring the Bioengineering of Cognitive Enhancement and Mental Health Optimization.Bioengineering (Basel, Switzerland) · 2025Review
- A systematic review of passive data for remote monitoring in psychosis and schizophrenia.NPJ digital medicine · 2025Article
- Multimodal Mental Health Digital Biomarker Analysis From Remote Interviews Using Facial, Vocal, Linguistic, and Cardiovascular Patterns.IEEE journal of biomedical and health informatics · 2024Article
- Accessibility and availability of smartphone apps for schizophrenia.Schizophrenia (Heidelberg, Germany) · 2022Article
- Multimodal Assessment of Schizophrenia and Depression Utilizing Video, Acoustic, Locomotor, Electroencephalographic, and Heart Rate Technology: Protocol for an Observational Study.JMIR research protocols · 2022Article
- Characterization of activity behavior using a digital medicine system and comparison to medication ingestion in patients with serious mental illness.NPJ digital medicine · 2021Article
- Using behavioral rhythms and multi-task learning to predict fine-grained symptoms of schizophrenia.Scientific reports · 2020Article
- Altered Autonomic Function in Individuals at Clinical High Risk for Psychosis.Frontiers in psychiatry · 2020Article
- Entropy analysis of heart rate variability and its application to recognize major depressive disorder: A pilot study.Technology and health care : official journal of the European Society for Engineering and Medicine · 2019Article
- Multiscale network dynamics between heart rate and locomotor activity are altered in schizophrenia.Physiological measurement · 2018Article
- A review of physiological and behavioral monitoring with digital sensors for neuropsychiatric illnesses.Physiological measurement · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveSchizophrenia has been associated with changes in heart rate (HR) and physical activity measures. However, the relationship between analysis window length and classifier accuracy using these features has yet to be quantified. APPROACH: Here we used objective HR and activity data to classify contiguous days of data as belonging to a schizophrenia patient or a healthy control. HR and physical activity recordings were made on 12 medicated subjects with schizophrenia and 12 healthy controls. Features derived from these data included classical statistical characteristics, rest-activity metrics, transfer entropy, and multiscale fuzzy entropy. We varied the analysis window length from two to eight days, and selected features via minimal-redundancy-maximal-relevance. A support vector machine was trained to classify schizophrenia from control windows on a daily basis. Model performance was assessed via subject-wise leave-one-out-crossfold-validation. MAIN
resultsAn analysis window length of eight days resulted in an area under a receiver operating characteristic curve (AUC) of 0.96. Reducing the analysis window length to two days only lowered the AUC to 0.91. The type of most predictive features varied with analysis window length. SIGNIFICANCE: Our results suggest continuous tracking of subjects with schizophrenia over short time scales may be sufficient to estimate illness severity on a daily basis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.