Evidence map›Paper›PMID 28653624›Full record

ArticleeLife2017

Parallel evolution of influenza across multiple spatiotemporal scales.

Katherine S Xue, Terry Stevens-Ayers, Angela P Campbell, Janet A Englund, Steven A Pergam, Michael Boeckh, Jesse D Bloom

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. The potential impacts of human genetics on virus emergence.Proceedings of the National Academy of Sciences of the United States of America · 2025
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katherine S XueDepartment of Genome Sciences, University of Washington, Seattle, United States.ORCID 0000-0002-4094-3615
Terry Stevens-AyersVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Angela P CampbellVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Janet A EnglundSeattle Children's Research Institute, Seattle, United States.
Steven A PergamVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Michael BoeckhVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Jesse D BloomDepartment of Genome Sciences, University of Washington, Seattle, United States.ORCID 0000-0003-1267-3408

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KOOPMAN, JAMES STEPHEN · 2014 to 2018
$12.5M
Respiratory Viruses and Airflow Obstruction after HCTR01HL081595 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BOECKH, MICHAEL J · 2005 to 2008
$2.5M
High-throughput experiments to guide influenza vaccine strain selectionR01AI127893 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BLOOM, JESSE D · 2016 to 2020
$2.1M
Mapping epistasis in molecular evolution: the influenza nucleoproteinR01GM102198 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BLOOM, JESSE D · 2012 to 2016
$1.6M
Infections in Hematopoietic Cell Transplant RecipientsK24HL093294 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BOECKH, MICHAEL J · 2009 to 2019
$1.5M
Parainfluenza Virus Infection in Hematopoietic Cell Transplant RecipientsK23HL091059 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI CAMPBELL, ANGELA JEAN PECK · 2008 to 2012
$682k
Howard Hughes Medical InstituteNHLBI NIH HHS K23 HL091059NHLBI NIH HHS K24 HL093294NHLBI NIH HHS R01 HL081595NIAID NIH HHS R01 AI127893NIGMS NIH HHS R01 GM102198NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

Viral variants that arise in the global influenza population begin as

Indexed as

Evolution, MolecularGenetic VariationAdultAgedFemaleHigh-Throughput Nucleotide SequencingHumansImmunocompromised HostInfluenza A Virus, H3N2 SubtypeInfluenza, HumanLongitudinal StudiesMaleMiddle AgedMutationRNA, ViralSequence Analysis, DNARNA, Viralantigenic evolutionclonal interferencedeep sequencingepidemiologyevolutionary biologygenomicshemagglutininhumaninfectious diseaseinfluenzamicrobiologyvirus

Identifiers

PMID28653624
PMCPMC5487208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.