Evidence map›Paper›PMID 28653600›Full record

ArticleOncology research2018

miR-205 Inhibits Neuroblastoma Growth by Targeting cAMP-Responsive Element-Binding Protein 1.

Shu Chen, Lianhua Jin, Shu Nie, Lizhi Han, Na Lu, Yan Zhou

Open access · hybridAbstract read
In one paragraph

Article in Oncology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Deciphering the Role of MicroRNAs in Neuroblastoma.Molecules (Basel, Switzerland) · 2021
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shu ChenDepartment of Thoracic Surgery, The Second Hospital of Jilin UniversityChangchunP.R. China.
Lianhua JinDepartment of Pediatrics, The First Hospital of Jilin UniversityChangchunP.R. China.
Shu NieDepartment of Pediatrics, The First Hospital of Jilin UniversityChangchunP.R. China.
Lizhi HanDepartment of Pediatrics, The First Hospital of Jilin UniversityChangchunP.R. China.
Na LuDepartment of Pediatrics, The First Hospital of Jilin UniversityChangchunP.R. China.
Yan ZhouDepartment of Pediatrics, The First Hospital of Jilin UniversityChangchunP.R. China.
First Hospital of Jilin University · CNJilin University · CNSecond Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence indicates that microRNA-205 (miR-205) is involved in tumor initiation, development, and metastasis in various cancers. However, its functions in neuroblastoma (NB) remain largely unclear. Here we found that miR-205 was significantly downregulated in human NB tissue samples and cell lines. miR-205 expression was lower in poorly differentiated NB tissues and those of advanced International Neuroblastoma Staging System stage. In addition, restoration of miR-205 in NB cells suppressed proliferation, migration, and invasion and induced cell apoptosis in vitro, as well as impaired tumor growth in vivo. cAMP-responsive element-binding protein 1 (

Indexed as

Gene Expression Regulation, NeoplasticAnimalsApoptosisBiomarkers, TumorCase-Control StudiesCell MovementCell ProliferationCyclic AMP Response Element-Binding ProteinHumansMaleMiceMice, Inbred BALB CMice, NudeMicroRNAsNeuroblastomaPrognosisBiomarkers, TumorCREB1 protein, humanCyclic AMP Response Element-Binding ProteinMicroRNAsMIR205, human

Identifiers

PMID28653600
PMCPMC7844742
OpenAlexW2899371638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.