Evidence map›Paper›PMID 28653584›Full record

ArticleJournal for immunotherapy of cancer2017

Immunotherapy biomarkers 2016: overcoming the barriers.

James L Gulley, Jay A Berzofsky, Marcus O Butler, Alessandra Cesano, Bernard A Fox, Sacha Gnjatic, Sylvia Janetzki, Shyam Kalavar, Vaios Karanikas, Samir N Khleif and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal for immunotherapy of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. A Serum-Induced Transcriptome and Serum Cytokine Signature Obtained at Diagnosis Correlates with the Development of Early Pancreatic Ductal Adenocarcinoma Metastasis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

James L GulleyGenitourinary Malignancies Branch, Center for Cancer Research, NCI, 10 Center Dr., 13 N240, Bethesda, MD, 20892, USA.
Jay A BerzofskyVaccine Branch, Center for Cancer Research, 41 Medlars Dr, Bldg 41 Rm D702D, Bethesda, MD, 20892, USA.
Marcus O ButlerPrincess Margaret Cancer Center/Ontario Cancer Institute, RM 9-622, 610 University Ave, Toronto, ON, Canada.
Alessandra CesanoNanoString, Inc., 500 Fairview Avenue North, Seattle, WA, 98109, USA.
Bernard A FoxEarle A. Chiles Research Institute, Providence Cancer Center, 4805 NE Glisan Street, Portland, OR, 97213, USA.
Sacha GnjaticDepartment of Hematology/Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, S5-105, 1470 Madison Avenue, Box 1128, New York, NY, 10029, USA.
Sylvia JanetzkiZellNet Consulting, Inc., 555 North Avenue, Fort Lee, NJ, 07024, USA.
Shyam KalavarCenter for Devices and Radiological Health, U.S. Food and Drug Administration, 1401 Rockville Pike, Rockville, MD, 20852, USA.
Vaios KaranikasRoche Innovation Center Zurich, Wagistrasse 18, Schlieren, Switzerland.
Samir N KhleifGeorgia Cancer Center, Augusta University, 1120 15th Street, CN-2101A, Augusta, GA, 30912, USA.
Ilan KirschAdaptive Biotechnologies, Inc., 1551 Eastlake Ave. E., Seattle, WA, 98102, USA.
Peter P LeeDepartment of Immuno-oncology, City of Hope, 1500 East Duarte Road, Duarte, CA, 91010, USA.
Cristina MaccalliDepartment of Translational Medicine, Sidra Medical and Research Center, Doha, Qatar.
Holden MaeckerStanford University Medical Center, 299 Campus Drive, Stanford, CA, 94303, USA.
Jeffrey SchlomNational Cancer Institute, National Institutes of Health, 10 Center Drive, Bldg. 10, Room 8B09, Bethesda, MD, 20892, USA.
Barbara SeligerInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Magdeburger Str. 2, Halle, Germany.
Janet SiebertCytoAnalytics, 3500 South Albion Street, Cherry Hills Village, CO, 80113, USA.
David F StroncekDepartment of Transfusion Medicine, National Institutes of Health, 10 Center Drive, Building 10, Room 3C720, Bethesda, MD, 20892, USA.
Magdalena ThurinNational Cancer Institute, Cancer Diagnosis Program, DCTD, National Institutes of Health, 9609 Medical Center Drive, Bethesda, 20892, MD, USA.
Jianda YuanEarly Clinical Oncology Development, Merck Research Laboratories, Rahway, NJ, 07065, USA.
Lisa H ButterfieldDepartment of Medicine, Surgery and Immunology, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Pittsburgh, PA, 15213, USA. butterfieldl@upmc.edu.

Funding

Clinical trials employing cancer vaccine combination therapiesZIABC010945 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GULLEY, JAMES L. · 2009 to 2022
$9.6M
Develop novel assays for assessing cellular and gene therapiesZIACL002119 · CLC · CLINICAL CENTER · PI STRONCEK, DAVID · 2010 to 2025
$0k
6 · The paper itself

Abstract

This report summarizes the symposium, 'Immunotherapy Biomarkers 2016: Overcoming the Barriers', which was held on April 1, 2016 at the National Institutes of Health in Bethesda, Maryland. The symposium, cosponsored by the Society for Immunotherapy of Cancer (SITC) and the National Cancer Institute (NCI), focused on emerging immunotherapy biomarkers, new technologies, current hurdles to further progress, and recommendations for advancing the field of biomarker development.

Indexed as

Biomarkers, TumorCongresses as TopicHumansImmunotherapyMarylandNational Cancer Institute (U.S.)NeoplasmsTumor MicroenvironmentUnited StatesBiomarkers, TumorBaseline measuresBiomarkersHigh throughputImmune monitoringImmunotherapyTumor microenvironment

Identifiers

PMID28653584
PMCPMC5359902

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.