Evidence map›Paper›PMID 28653289›Full record

ArticleCellular oncology (Dordrecht, Netherlands)2017

Histamine H

Abdelhakim Salem, Rabeia Almahmoudi, Dyah Listyarifah, Maria Siponen, Katariina Maaninka, Ahmed Al-Samadi, Tuula Salo, Kari K Eklund

Open access · greenAbstract read
In one paragraph

Article in Cellular oncology (Dordrecht, Netherlands), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Histamine receptors and cancer pharmacology: an update.British journal of pharmacology · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Activation of histamine HJournal of molecular medicine (Berlin, Germany) · 2018
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Abdelhakim SalemDepartment of Clinical Medicine, Clinicum, University of Helsinki, Helsinki, Finland. Abdelhakim.Salem@helsinki.fi.
Rabeia AlmahmoudiDepartment of Oral and Maxillofacial Diseases, Clinicum, University of Helsinki, Haartmaninkatu 8, Biomedicum Helsinki 1, PO Box 63, FI-00029 HUS, Helsinki, Finland.
Dyah ListyarifahDepartment of Clinical Medicine, Clinicum, University of Helsinki, Helsinki, Finland.
Maria SiponenDepartment of Oral and Maxillofacial Diseases, Kuopio University Hospital, Kuopio, Finland.
Katariina MaaninkaWihuri Research Institute, Biomedicum Helsinki, Helsinki, Finland.
Ahmed Al-SamadiDepartment of Oral and Maxillofacial Diseases, Clinicum, University of Helsinki, Haartmaninkatu 8, Biomedicum Helsinki 1, PO Box 63, FI-00029 HUS, Helsinki, Finland.
Tuula SaloDepartment of Oral and Maxillofacial Diseases, Clinicum, University of Helsinki, Haartmaninkatu 8, Biomedicum Helsinki 1, PO Box 63, FI-00029 HUS, Helsinki, Finland.
Kari K EklundDepartment of Clinical Medicine, Clinicum, University of Helsinki, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FIKuopio University Hospital · FIUniversity of Oulu · FIWihuri Research Institute · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent reports indicate that histamine and its novel, high-affinity histamine H

methodsBiopsies taken from OED, OTSCC and healthy oral mucosa were studied by immunostaining. Primary human oral keratinocytes (HOKs) and two OTSCC-derived cell lines (HSC-3 and SCC-25) were used for the in vitro studies. Quantitative real-time PCR was used to measure oncogene expression in the stimulated HOKs.

resultsWe found that H

conclusionsOur results suggest an association between H

Indexed as

FemaleHumansImmunohistochemistryIn Vitro TechniquesMaleMiddle AgedMouth NeoplasmsReal-Time Polymerase Chain ReactionReceptors, Histamine H4Tongue NeoplasmsTumor Cells, CulturedReceptors, Histamine H4HistamineHistamine H4 receptorMast cellsOral cancerOral epithelial dysplasiaOral tongue squamous cell carcinoma

Identifiers

PMID28653289
PMCPMC13001584
OpenAlexW2682067394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.