Evidence map›Paper›PMID 28653263›Full record

ArticleClinical rheumatology2017

Standardizing and personalizing the treat to target (T2T) approach for rheumatoid arthritis using the Patient-Reported Outcomes Measurement Information System (PROMIS): baseline findings on patient-centered treatment priorities.

Emily J Bacalao, George J Greene, Jennifer L Beaumont, Amy Eisenstein, Azra Muftic, Arthur M Mandelin, David Cella, Eric M Ruderman

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The use of PROMIS measures in clinical studies in patients with inflammatory arthritis: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Pooled it
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  8. Observational
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  12. Intra-articular use of radium dichloride ([European journal of nuclear medicine and molecular imaging · 2021
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  14. Is a treat-to-target strategy in osteoporosis applicable in clinical practice? Consensus among a panel of European experts.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  15. Review
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  18. Challenges in Implementing Treat-to-Target Strategies in Rheumatology.Rheumatic diseases clinics of North America · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emily J BacalaoDepartment of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, NMH/Galter Room 14-100, 675 N. St. Clair, Chicago, IL, 60611, USA.
George J GreeneDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jennifer L BeaumontDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Amy EisensteinDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Azra MufticDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Arthur M MandelinDepartment of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, NMH/Galter Room 14-100, 675 N. St. Clair, Chicago, IL, 60611, USA.
David CellaDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Eric M RudermanDepartment of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, NMH/Galter Room 14-100, 675 N. St. Clair, Chicago, IL, 60611, USA. e-ruderman@northwestern.edu.ORCID http://orcid.org/0000-0002-1791-8729

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A treat to target (T2T) approach to management has become the standard of care for patients with rheumatoid arthritis (RA). While consensus T2T recommendations call for patient involvement in the treatment process, the targets commonly used to drive therapeutic decisions involve limited patient input. A pilot study was developed to explore whether the Patient-Reported Outcomes Measurement Information System (PROMIS) could add value to the T2T approach by providing a way to bring patient goals into the process. We report here the baseline data from this study. RA patients from an academic rheumatology practice were recruited to participate in this 1-year study. Patients were asked to complete PROMIS computer-assisted testing at quarterly visits during the year. At baseline, they were asked to identify the PROMIS domain (Pain Interference, Fatigue, Depression, Physical Function, and Social Function) that felt most important to their quality of life. They were then asked to select five representative items from this domain, to be followed through the year. Complete baseline data was available for 119 patients. Most selected Physical Function (39%) or Pain Interference (37%) as their highest priority PROMIS domain. Sixty percent ranked Depression as their lowest priority domain. Younger patients more frequently prioritized Social Function, while older patients more frequently prioritized Fatigue. The incorporation of PROMIS questionnaires into routine clinic visits is a feasible mechanism for incorporating patient preferences into a T2T approach to managing RA.

Indexed as

Patient ParticipationPatient Reported Outcome MeasuresAdultAgedAntirheumatic AgentsArthritis, RheumatoidDepressionFatigueFemaleHumansMaleMiddle AgedPainPilot ProjectsQuality of LifeSeverity of Illness IndexAntirheumatic AgentsPROMISRheumatoid arthritisTreat to target

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.