Evidence map›Paper›PMID 28653013›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2017

Estimation of signal and noise for a whole-body research photon-counting CT system.

Zhoubo Li, Shuai Leng, Zhicong Yu, Steffen Kappler, Cynthia H McCollough

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zhoubo LiMayo Clinic, Department of Radiology, Rochester, Minnesota, United States.
Shuai LengMayo Clinic, Department of Radiology, Rochester, Minnesota, United States.
Zhicong YuMayo Clinic, Department of Radiology, Rochester, Minnesota, United States.
Steffen KapplerSiemens Healthcare, Forchheim, Bavaria, Germany.
Cynthia H McColloughMayo Clinic, Department of Radiology, Rochester, Minnesota, United States.
Mayo Clinic · USSiemens Healthcare (Germany) · DE

Funding

Photon-Counting Spectral CT to Reduce Dose and Detect Early Vascular DiseaseR01EB016966 · NIBIB · MAYO CLINIC ROCHESTER · PI MCCOLLOUGH, CYNTHIA H · 2013 to 2017
$5.1M
EXTRAMURAL RES FACIL IMPROVEMENT PROG: POLYCYSTIC KIDNEY DISEASE, RENAL STUDIES,C06RR018898 · NCRR · MAYO CLINIC · PI BURNETT, JOHN C · 2004 to 2004
$2.3M
NCRR NIH HHS C06 RR018898NIBIB NIH HHS R01 EB016966
6 · The paper itself

Abstract

Photon-counting detector CT has a large number of acquisition parameters that require optimization, particularly the energy threshold configurations. Fast and accurate estimation of both signal and noise in photon-counting CT (PCCT) images can facilitate such optimization. Using the detector response function of a research PCCT system, we derived mathematical models for both signal and noise estimation, taking into account beam spectrum and filtration, object attenuation, water beam hardening, detector response, radiation dose, energy thresholds, and the propagation of noise. To determine the absolute noise value, a noise lookup table (LUT) for all available energy thresholds was acquired using a number of calibration scans. The noise estimation algorithm then used the noise LUT to estimate noise for scans with a variety of combination of energy thresholds, dose levels, and object attenuations. Validation of the estimation algorithms was performed on a whole-body research PCCT system using semianthropomorphic water phantoms and solutions of calcium and iodine. Clinical feasibility of noise estimation was assessed with scans of a cadaver head and a living swine. The algorithms achieved accurate estimation of both signal and noise for a variety of scanning parameter combinations. Maximum discrepancies were below 15%, while most errors were below 5%.

Indexed as

CTenergy threshold configurationsmultienergy CTphoton-counting detectorsignal and noise estimation

Identifiers

PMID28653013
PMCPMC5480253
OpenAlexW2721208987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.