ArticleHepatobiliary surgery and nutrition2017
Association of primary tumor lymph node ratio with burden of liver metastases and survival in stage IV colorectal cancer.
Article in Hepatobiliary surgery and nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed.
- Prognostic nomogram to predict the overall survival of patients with early-onset colorectal cancer: a population-based analysis.International journal of colorectal disease · 2021Trial
- Lymph node ratio and overall survival in patients with colon cancer: a prospective multicentre cohort study.Scientific reports · 2026Article
- Prognostic model for early-onset colorectal cancer with liver metastasis after primary tumor resection and chemotherapy.Scientific reports · 2025Article
- Review
- Prediction model of colorectal cancer (CRC) lymph node metastasis based on intestinal bacteria.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Article
- Development and validation of a clinical survival model for young-onset colorectal cancer with synchronous liver-only metastases: a SEER population-based study and external validation.Frontiers in oncology · 2023Article
- Prognostic Value of Lymph Node Ratio in Patients with Resected Synchronous Colorectal Liver Metastases and Less Than 12 Examined Lymph Nodes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Beyond N staging in colorectal cancer: Current approaches and future perspectives.Frontiers in oncology · 2022Review
- The role of myeloid-derived suppressor cells in gastrointestinal cancer.Cancer communications (London, England) · 2021Review
- Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps.Oncology and therapy · 2021Review
- Nodal grouping in nasopharyngeal carcinoma: prognostic significance, N classification, and a marker for the identification of candidates for induction chemotherapy.European radiology · 2020Article
- OTUB1 Recruits Tumor Infiltrating Lymphocytes and Is a Prognostic Marker in Digestive Cancers.Frontiers in molecular biosciences · 2020Article
- Hepatobiliary case report and literature review of hepatic reactive lymphoid hyperplasia with positive anti-smooth muscle antibody and anti-nuclear antibody tests.Translational cancer research · 2019Article
- Prognostic value of the metastatic lymph node ratio in patients with pancreatic cancer.International journal of clinical and experimental pathology · 2019Article
- Association between the lymph node ratio and hepatic tumor burden: importance for resectable colorectal liver metastases?Hepatobiliary surgery and nutrition · 2018Article
- Primary lymph node ratio and hepatic resection for colorectal metastases.Hepatobiliary surgery and nutrition · 2018Article
- Lymph node ratio as a valuable prognostic factor for patients with colorectal liver-only metastasis undergoing curative resection.Cancer management and research · 2018Article
- PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy.Journal of hematology & oncology · 2017Review
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6 authors.
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Abstract
backgroundThe primary objective of our study was to assess the association of primary tumor lymph node ratio (LNR) in stage IV colorectal adenocarcinomas (CRC) with overall survival (OS) and the extent of metastatic disease in the liver.
methodsWe analyzed data on 53 stage IV CRC patients who underwent surgical resection of the primary tumor. The median LNR of 0.25 was used to stratify patients into high LNR (H-LNR) and low LNR (L-LNR) groups. Statistical comparison was performed using chi square test and multiple regression models. OS was calculated using the Kaplan-Meier (KM) method while cox regression was used for multivariate analysis.
resultsH-LNR status was associated with the presence of >3 liver metastases (LM) [odds ratio (OR): 2.43, P=0.047] and bilobar LM (OR: 3.94, P=0.039). The OS in H-LNR patients was significantly worse in the entire cohort compared to L-LNR (9%
conclusionsIn stage IV CRC, LNR is associated with the extent of hepatic tumor burden and was an independent predictor of survival in patients undergoing liver resection.
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