Evidence map›Paper›PMID 28652709›Full record

ArticleDrug design, development and therapy2017

Efficacy of antibiotic treatment of implant-associated

Felix Greimel, Christine Scheuerer, Andre Gessner, Michaela Simon, Thomas Kalteis, Joachim Grifka, Achim Benditz, Hans-Robert Springorum, Jens Schaumburger

Open access · goldAbstract readComparative Study
In one paragraph

Article in Drug design, development and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Rifampin Based Therapy for Patients With Staphylococcus aureus Native Vertebral Osteomyelitis: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Staphylococcus aureus vertebral osteomyelitis: a single-centre retrospective cohort study with focus on oral flucloxacillin follow-up.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  6. Fluoroquinolones and Biofilm: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
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  16. Review
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  20. Future directions of postoperative spinal implant infections.Journal of spine surgery (Hong Kong) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Felix GreimelDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Christine ScheuererDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Andre GessnerInstitute of Clinical Microbiology and Hygiene, University Medical Center Regensburg, Regensburg, Bavaria, Germany.
Michaela SimonInstitute of Clinical Microbiology and Hygiene, University Medical Center Regensburg, Regensburg, Bavaria, Germany.
Thomas KalteisDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Joachim GrifkaDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Achim BenditzDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Hans-Robert SpringorumDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Jens SchaumburgerDepartment of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach.
Asklepios Kliniken Bad Abbach · DEInstitute of Medical Microbiology and Hygiene · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of antibiotic monotherapy and combination therapy in the treatment of implant-associated infection by

Indexed as

AnimalsAnti-Bacterial AgentsBacterial LoadBiofilmsColony Count, MicrobialDisease Models, AnimalDrug Resistance, BacterialDrug Therapy, CombinationFloxacillinFluoroquinolonesJoint ProsthesisMaleMoxifloxacinProsthesis-Related InfectionsRats, WistarRifampinAnti-Bacterial AgentsFloxacillinFluoroquinolonesMoxifloxacinRifampinflucloxacillinimplant-associated infectionmoxifloxacinprosthetic infectionrifampinStaphylococcus aureus

Identifiers

PMID28652709
PMCPMC5476658
OpenAlexW2626636251

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.