ArticleThe Journal of cell biology1985
Non-spindle microtubule organizing centers in metaphase II-arrested mouse oocytes.
Article in The Journal of cell biology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 253 citations in OpenAlex.
- Whole-Mount Immunofluorescence Staining to Visualize Cell Cycle Progression in Mouse Oocyte Meiosis.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Predicting Infertility: How Genetic Variants in Oocyte Spindle Genes Affect Egg Quality.Advances in anatomy, embryology, and cell biology · 2024Review
- Multiple asters organize the yolk microtubule network during dclk2-GFP zebrafish epiboly.Scientific reports · 2022Article
- Stable kinetochore-microtubule attachments restrict MTOC position and spindle elongation in oocytes.EMBO reports · 2021Article
- CEP215 and AURKA regulate spindle pole focusing and aMTOC organization in mouse oocytes.Reproduction (Cambridge, England) · 2020Article
- Chromosome structural anomalies due to aberrant spindle forces exerted at gene editing sites in meiosis.The Journal of cell biology · 2018Article
- Functions and dysfunctions of the mammalian centrosome in health, disorders, disease, and aging.Histochemistry and cell biology · 2018Review
- Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse.Scientific reports · 2018Article
- Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment.EMBO reports · 2018Article
- Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes.The Journal of cell biology · 2017Article
- Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes.Cell cycle (Georgetown, Tex.) · 2017Article
- Error-prone meiotic division and subfertility in mice with oocyte-conditional knockdown of pericentrin.Journal of cell science · 2017Article
- KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte.Scientific reports · 2016Article
- The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes.Scientific reports · 2016Article
- Oocyte Maturation and Development.F1000Research · 2016Review
- Pre-implantation developmental potential from in vivo and in vitro matured mouse oocytes: a cytoskeletal perspective on oocyte quality.Journal of assisted reproduction and genetics · 2015Article
- Depletion of pericentrin in mouse oocytes disrupts microtubule organizing center function and meiotic spindle organization.Molecular reproduction and development · 2014Article
- Perturbing microtubule integrity blocks AMP-activated protein kinase-induced meiotic resumption in cultured mouse oocytes.Zygote (Cambridge, England) · 2014Article
- The transcription factor Egr3 is a putative component of the microtubule organizing center in mouse oocytes.PloS one · 2014Article
- Spindle formation in the mouse embryo requires Plk4 in the absence of centrioles.Developmental cell · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A human autoantiserum (5051) directed against pericentriolar material (PCM) was used to study the distribution of microtubule-organizing centers (MTOCs) in the oocyte and during the first cell cycle of mouse development. In oocytes, the PCM was found not only at the poles of the barrel-shaped metaphase II spindle but also at many discrete loci around the cytoplasm near the cell cortex. The spindle poles were also composed of several PCM foci. In metaphase-arrested eggs only the PCM foci located near the chromosomes acted as MTOCs. However, after reduction of the critical concentration for tubulin polymerization by taxol, the cytoplasmic PCM foci were also found to be associated with nucleation of microtubules. After fertilization the cortical PCM foci remained in a peripheral position until the end of the S phase, when they appeared to migrate centrally towards the pronuclei. At prometaphase of the first mitotic division, numerous MTOCs were found around the two sets of chromosomes; these MTOCs then aligned to form two bands on either side of the metaphase plate of the first mitosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.