ArticleScientific reports2017
Testing hypotheses of developmental constraints on mammalian brain partition evolution, using marsupials.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Cranial anatomy, palaeoneurology, palaeobiology and stratigraphic age of the large-bodied ornithopod,PeerJ · 2026Article
- The geometry of life: testing the scaling of whole-organism surface area and volume using sharks.Royal Society open science · 2025Article
- Divergent patterns of cranial suture fusion in marsupial and placental mammals.Zoological journal of the Linnean Society · 2025Article
- Avian telencephalon and cerebellum volumes can be accurately estimated from digital brain endocasts.Biology letters · 2025Article
- Brain shapes of large-bodied, flightless ratites (Aves: Palaeognathae) emerge through distinct developmental allometries.Royal Society open science · 2024Article
- Differential developmental rates and demographics in Red Kangaroo (Journal of mammalogy · 2023Article
- Clade-specific forebrain cytoarchitectures of the extinct Tasmanian tiger.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- An agent-based model clarifies the importance of functional and developmental integration in shaping brain evolution.BMC biology · 2021Article
- Testing hypotheses of marsupial brain size variation using phylogenetic multiple imputations and a Bayesian comparative framework.Proceedings. Biological sciences · 2021Article
- Mandibular musculature constrains brain-endocast disparity between sarcopterygians.Royal Society open science · 2020Article
- Comparative growth in the olfactory system of the developing chick with considerations for evolutionary studies.Journal of anatomy · 2020Article
- Co-evolution of cerebral and cerebellar expansion in cetaceans.Journal of evolutionary biology · 2019Article
- Primate hippocampus size and organization are predicted by sociality but not diet.Proceedings. Biological sciences · 2019Article
- Interindividual Variability of Functional Connectivity in Awake and Anesthetized Rhesus Macaque Monkeys.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019Article
- A fly in a tube: Macroevolutionary expectations for integrated phenotypes.Evolution; international journal of organic evolution · 2018Review
- Development and Evolution of Cerebral and Cerebellar Cortex.Brain, behavior and evolution · 2018Review
- Re-evaluating the link between brain size and behavioural ecology in primates.Proceedings. Biological sciences · 2017Article
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7 authors.
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Abstract
There is considerable debate about whether the partition volumes of the mammalian brain (e.g. cerebrum, cerebellum) evolve according to functional selection, or whether developmental constraints of conserved neurogenetic scheduling cause predictable partition scaling with brain size. Here we provide the first investigation of developmental constraints on partition volume growth, derived from contrast-enhanced micro-computed tomography of hydrogel-stabilized brains from three marsupial species. ANCOVAs of partition vs. brain volume scaling, as well as growth curve comparisons, do not support several hypotheses consistent with developmental constraints: brain partition growth significantly differs between species, or between developing vs. adult marsupials. Partition growth appears independent of adult brain volume, with no discernable growth spurts/lags relatable to internal structural change. Rather, adult proportion differences appear to arise through growth rate/duration heterochrony. Substantial phylogenetic signal in adult brain partitions scaling with brain volume also counters expectations of development-mediated partition scaling conservatism. However, the scaling of olfactory bulb growth is markedly irregular, consistent with suggestions that it is less constrained. The very regular partition growth curves suggest intraspecific developmental rigidity. We speculate that a rigid, possibly neuromer-model-like early molecular program might be responsible both for regular growth curves within species and impressions of a link between neurogenesis and partition evolution.
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