Evidence map›Paper›PMID 28652388›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2017

Optimization of Thermolytic Response to A

Isaac R Bailey, Bernard Laughlin, Lucille A Moore, Lori K Bogren, Zeinab Barati, Kelly L Drew

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. NExperimental neurology · 2024
    Article
  2. Characterization and Seasonal Modulation of Adenosine AInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Shallow metabolic depression and human spaceflight: a feasible first step.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Article
  5. Non-Nucleoside Agonists of the Adenosine Receptors: An Overview.Pharmaceuticals (Basel, Switzerland) · 2019
    Review
  6. Precise Control of Target Temperature Using NTherapeutic hypothermia and temperature management · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Isaac R BaileyInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., L.A.M., L.K.B., Z.B., K.L.D.); and Departments of Chemistry and Biochemisty, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., K.L.D.).
Bernard LaughlinInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., L.A.M., L.K.B., Z.B., K.L.D.); and Departments of Chemistry and Biochemisty, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., K.L.D.).
Lucille A MooreInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., L.A.M., L.K.B., Z.B., K.L.D.); and Departments of Chemistry and Biochemisty, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., K.L.D.).
Lori K BogrenInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., L.A.M., L.K.B., Z.B., K.L.D.); and Departments of Chemistry and Biochemisty, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., K.L.D.).
Zeinab BaratiInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., L.A.M., L.K.B., Z.B., K.L.D.); and Departments of Chemistry and Biochemisty, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., K.L.D.).
Kelly L DrewInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., L.A.M., L.K.B., Z.B., K.L.D.); and Departments of Chemistry and Biochemisty, University of Alaska Fairbanks, Fairbanks, Alaska (I.R.B., B.L., K.L.D.) kdrew@alaska.edu.
University of Alaska Fairbanks · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
Targeting Central A1 Adenosine Receptors Induces Hypothermia for StrokeR15NS070779 · NINDS · UNIVERSITY OF ALASKA FAIRBANKS · PI DREW, KELLY L · 2010 to 2014
$949k
NIGMS NIH HHS P20 GM103395NINDS NIH HHS R15 NS070779
6 · The paper itself

Abstract

Cardiac arrest is a leading cause of death in the United States, and, currently, therapeutic hypothermia, now called targeted temperature management (TTM), is the only recent treatment modality proven to increase survival rates and reduce morbidity for this condition. Shivering and subsequent metabolic stress, however, limit application and benefit of TTM. Stimulating central nervous system A

Indexed as

AdenosineAdenosine A1 Receptor AgonistsAminopyridinesAnimalsDose-Response Relationship, DrugFeeding BehaviorHibernationHypothermia, InducedMaleOxygen ConsumptionRatsRats, Sprague-DawleyShiveringThermogenesisThiazolesAdenosineAdenosine A1 Receptor AgonistsAminopyridinescapadenosonN(6)-cyclohexyladenosineThiazoles

Identifiers

PMID28652388
PMCPMC5539588
OpenAlexW2686605968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.