Evidence map›Paper›PMID 28652371›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Microfluidic guillotine for single-cell wound repair studies.

Lucas R Blauch, Ya Gai, Jian Wei Khor, Pranidhi Sood, Wallace F Marshall, Sindy K Y Tang

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

  1. A role for theMolecular biology of the cell · 2026
    Article
  2. A role for thebioRxiv : the preprint server for biology · 2025
    Article
  3. Characterization of cellular wound resistance in the giant ciliatebioRxiv : the preprint server for biology · 2025
    Article
  4. Physical Forces in Regeneration of Cells and Tissues.Cold Spring Harbor perspectives in biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lucas R BlauchDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Ya GaiDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Jian Wei KhorDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Pranidhi SoodDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA 94143.
Wallace F MarshallDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA 94143.
Sindy K Y TangDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305; sindy@stanford.edu.ORCID 0000-0003-1465-2432
Stanford University · USUniversity of California, San Francisco · US

Funding

Graduate Training Program in BiotechnologyT32GM008412 · NIGMS · STANFORD UNIVERSITY · PI COCHRAN, JENNIFER R · 1991 to 2020
$5.5M
Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational ApproachesR13GM085967 · NIGMS · MARINE BIOLOGICAL LABORATORY · PI FLETCHER, DANIEL A, HYMAN, LINDA E · 2008 to 2019
$1.7M
Pattern formation and regeneration in a single cellR01GM113602 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARSHALL, WALLACE · 2015 to 2018
$1.6M
NIGMS NIH HHS R01 GM113602NIGMS NIH HHS R13 GM085967NIGMS NIH HHS T32 GM008412
6 · The paper itself

Abstract

Wound repair is a key feature distinguishing living from nonliving matter. Single cells are increasingly recognized to be capable of healing wounds. The lack of reproducible, high-throughput wounding methods has hindered single-cell wound repair studies. This work describes a microfluidic guillotine for bisecting single

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsAnimalsCell MembraneCiliophoraDimethylpolysiloxanesOocytesPressureReproducibility of ResultsTime FactorsViscosityWound HealingXenopusbaysilonDimethylpolysiloxanesmicrofluidicsmicroguillotinesingle cellStentor coeruleuswound healing

Identifiers

PMID28652371
PMCPMC5514750
OpenAlexW2678826551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.