ArticleProceedings of the National Academy of Sciences of the United States of America2017
Antagonistic BMP-cWNT signaling in the cnidarian
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Evolutionary rewiring of the endomesoderm gene regulatory networks specify skeleton secreting cells in stony corals.bioRxiv : the preprint server for biology · 2026Article
- Whole body regeneration deploys a rewired embryonic gene regulatory network logic.Nature communications · 2025Article
- Developmental system drift and modular gene regulatory networks shape gastrulation inLife science alliance · 2025Article
- FGF and BMP pathway genes are expressed in segmentally iterated domains during segmentation of germ layers in a tardigrade.bioRxiv : the preprint server for biology · 2025Article
- LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis.Neural development · 2024Article
- LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis.Research square · 2023Article
- BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians.PLoS genetics · 2023Article
- Cytoplasmic Polyadenylation Is an Ancestral Hallmark of Early Development in Animals.Molecular biology and evolution · 2023Article
- Muscle cell-type diversification is driven by bHLH transcription factor expansion and extensive effector gene duplications.Nature communications · 2023Article
- BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians.bioRxiv : the preprint server for biology · 2023Article
- Spatial transcriptomics reveals a conserved segment polarity program that governs muscle patterning inbioRxiv : the preprint server for biology · 2023Article
- Article
- The developmental biology ofScience advances · 2021Article
- FGF signaling acts on different levels of mesoderm development within Spiralia.Development (Cambridge, England) · 2021Article
- Does regeneration recapitulate phylogeny? Planaria as a model of body-axis specification in ancestral eumetazoa.Communicative & integrative biology · 2020Article
- The cadherin-catenin complex is necessary for cell adhesion and embryogenesis in Nematostella vectensis.Developmental biology · 2019Article
- Genomic analysis of the tryptome reveals molecular mechanisms of gland cell evolution.EvoDevo · 2019Article
- Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm.eLife · 2018Article
- Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation.Nature communications · 2018Article
- Germ-layer commitment and axis formation in sea anemone embryonic cell aggregates.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Gastrulation was arguably the key evolutionary innovation that enabled metazoan diversification, leading to the formation of distinct germ layers and specialized tissues. Differential gene expression specifying cell fate is governed by the inputs of intracellular and/or extracellular signals. Beta-catenin/Tcf and the TGF-beta bone morphogenetic protein (BMP) provide critical molecular signaling inputs during germ layer specification in bilaterian metazoans, but there has been no direct experimental evidence for a specific role for BMP signaling during endomesoderm specification in the early branching metazoan
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.