Evidence map›Paper›PMID 28652364›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

CIDE domains form functionally important higher-order assemblies for DNA fragmentation.

Jae Young Choi, Qi Qiao, Se-Hoon Hong, Chang Min Kim, Jae-Hee Jeong, Yeon-Gil Kim, Yong-Keun Jung, Hao Wu, Hyun Ho Park

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Novel Biallelic Variant in theFrontiers in genetics · 2022
    Article
  6. Article
  7. Article
  8. The role of the DFF40/CAD endonuclease in genomic stability.Apoptosis : an international journal on programmed cell death · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jae Young ChoiSchool of Chemistry and Biochemistry and Graduate School of Biochemistry, Yeungnam University, Gyeongsan 712-749, South Korea.
Qi QiaoDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Se-Hoon HongSchool of Biological Science, Seoul National University, Seoul 151-747, South Korea.
Chang Min KimSchool of Chemistry and Biochemistry and Graduate School of Biochemistry, Yeungnam University, Gyeongsan 712-749, South Korea.
Jae-Hee JeongPohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 790-784, South Korea.
Yeon-Gil KimPohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 790-784, South Korea.
Yong-Keun JungSchool of Biological Science, Seoul National University, Seoul 151-747, South Korea.
Hao WuDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115; wu@crystal.harvard.edu hyunho@ynu.ac.kr.
Hyun Ho ParkSchool of Chemistry and Biochemistry and Graduate School of Biochemistry, Yeungnam University, Gyeongsan 712-749, South Korea; wu@crystal.harvard.edu hyunho@ynu.ac.kr.
Yeungnam University · KRBoston Children's Hospital · USPohang University of Science and Technology · KRSeoul National University · KR

Funding

SMOCs: Novel Signal Transduction Complexes as New Targets for Drug DiscoveryDP1HD087988 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI WU, HAO · 2015 to 2019
$4.4M
NICHD NIH HHS DP1 HD087988
6 · The paper itself

Abstract

Cell death-inducing DFF45-like effector (CIDE) domains, initially identified in apoptotic nucleases, form a family with diverse functions ranging from cell death to lipid homeostasis. Here we show that the CIDE domains of

Indexed as

DNA FragmentationAnimalsApoptosisApoptosis Regulatory ProteinsBinding SitesCell DeathCrystallography, X-RayDeoxyribonucleasesDrosophila melanogasterDrosophila ProteinsHomeostasisLipidsMiceMicroscopy, Electron, TransmissionMolecular ConformationMutationApoptosis Regulatory Proteinscaspase-activated deoxyribonucleasecaspase-activated DNase inhibitorDeoxyribonucleasesDFFB protein, humanDrep2 protein, DrosophilaDrep4 protein, DrosophilaDrosophila ProteinsLipidsPoly-ADP-Ribose Binding ProteinsProteinsapoptosisCIDE familyDNA fragmentationhigher-order structurelipid homeostasis

Identifiers

PMID28652364
PMCPMC5514754
OpenAlexW2630017584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.