Evidence map›Paper›PMID 28652310›Full record

ArticleInfection and immunity2017

Bacterial Nucleotidyl Cyclase Inhibits the Host Innate Immune Response by Suppressing TAK1 Activation.

Chenxi He, Yilong Zhou, Feng Liu, Haipeng Liu, Hao Tan, Shouguang Jin, Weihui Wu, Baoxue Ge

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. The journal of poultry science · 2026
    Article
  3. CombattingAntibiotics (Basel, Switzerland) · 2025
    Review
  4. iScience · 2025
    Article
  5. Assessing the Potential ofACS pharmacology & translational science · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Modulation of the immune response by theFrontiers in cellular and infection microbiology · 2022
    Review
  12. Article
  13. International journal of molecular sciences · 2021
    Review
  14. Prevalence of ExoY Activity inFrontiers in microbiology · 2021
    Article
  15. Review
  16. Review
  17. Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  18. Review
  19. TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages.Frontiers in cell and developmental biology · 2019
    Review
  20. The extreme C terminus of theThe Journal of biological chemistry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Chenxi HeShanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yilong ZhouShanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Feng LiuShanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Haipeng LiuShanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Hao TanState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Shouguang JinState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Weihui WuState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Baoxue GeShanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China gebaoxue@sibs.ac.cn.
Shanghai Pulmonary Hospital · CNState Key Laboratory of Medicinal Chemical BiologyNankai University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exoenzyme Y (ExoY) is a type III secretion system effector found in 90% of the

Indexed as

Host-Pathogen InteractionsImmune EvasionImmunity, InnateAnimalsBacterial ProteinsCell LineCytokinesDisease Models, AnimalFemaleGene DeletionGlucosyltransferasesHumansMAP Kinase Kinase Kinase 7MAP Kinase Kinase KinasesMice, Inbred C57BLNF-kappa BBacterial ProteinsCytokinesExoY protein, bacteriaGlucosyltransferasesMAP Kinase Kinase Kinase 7MAP Kinase Kinase KinasesNF-kappa BPhosphorus-Oxygen LyasesTranscription Factor AP-1ExoYMAPKsNF-κBnucleotidyl cyclaseproinflammatory cytokinesTAK1

Identifiers

PMID28652310
PMCPMC5563585
OpenAlexW2656688707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.