Evidence map›Paper›PMID 28652240›Full record

ArticleAntimicrobial agents and chemotherapy2017

The Nonantibiotic Macrolide EM703 Improves Survival in a Model of Quinolone-Treated Pseudomonas aeruginosa Airway Infection.

Gopinath Kasetty, Ravi K V Bhongir, Praveen Papareddy, Heiko Herwald, Arne Egesten

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Could Azithromycin Be Part ofFrontiers in microbiology · 2021
    Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gopinath KasettyRespiratory Medicine & Allergology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden gopinath.kasetty@med.lu.se.
Ravi K V BhongirRespiratory Medicine & Allergology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.ORCID 0000-0001-6648-1781
Praveen PapareddyInfection Medicine, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Heiko HerwaldInfection Medicine, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Arne EgestenRespiratory Medicine & Allergology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrolide antibiotics are used as anti-inflammatory agents, e.g., for prevention of exacerbations in chronic obstructive pulmonary disease and cystic fibrosis. Several studies have shown improved outcomes after the addition of macrolides to β-lactam antibiotics for treatment of severe community-acquired pneumonia. However, a beneficial effect of macrolides in treating Gram-negative bacterial airway infections, e.g., those caused by

Indexed as

AnimalsAnti-Bacterial AgentsBronchoalveolar Lavage FluidCytokinesDrug Therapy, CombinationErythromycinFemaleGastrointestinal TractLeukocyte CountLeukocytesLevofloxacinLungLung DiseasesMiceMice, Inbred BALB CNeutrophilsAnti-Bacterial AgentsCytokinesEM703ErythromycinLevofloxacinanti-inflammatoryEM703host defensemacrolidePseudomonas aeruginosa

Identifiers

PMID28652240
PMCPMC5571310
OpenAlexW2695494311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.