ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2017
Burden and Predictors of Poststroke Cognitive Impairment in a Sample of Ghanaian Stroke Survivors.
Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Comparisons of acupuncture therapies combining conventional treatment in the management of vascular cognitive impairment: a systematic review and network meta-analysis.Frontiers in aging neuroscience · 2025Pooled it
- Poststroke cognitive impairment among stroke survivors in Sub-Saharan Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Association between Blood Pressure and Post-Stroke Cognitive Impairment: A Meta-Analysis.Reviews in cardiovascular medicine · 2024Pooled it
- Tele-Rehabilitation after Stroke: An Updated Systematic Review of the Literature.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2018Pooled it
- Effect of a Cardiovascular Polypill on Poststroke Cognition Among Ghanaians: Secondary Analysis of a Randomized Clinical Trial.Journal of the American Heart Association · 2024Trial
- Correlation Between Serum TGF-β1 Levels, Intracranial Atherosclerotic Plaque Parameters and Post-Stroke Cognitive Impairment.International journal of general medicine · 2026Article
- Article
- Determinants of Cognitive Performance Among Ghanaian Hypertensive Patients: A Cross-Sectional Study.Health science reports · 2025Article
- Article
- Determinants of semantic and episodic memory decline among older adults in Ghana: Evidence from the WHO study on global AGEing and adult health Ghana wave 2.Dialogues in health · 2023Article
- Prevalence of suspected dementia in a sample of adults living in Kinshasa-Democratic Republic of the Congo.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Prevalence and predictors of post-stroke cognitive impairment among stroke survivors in Uganda.BMC neurology · 2023Article
- Prevalence and Predictors of Post-stroke Cognitive Impairment among Stroke Survivors in Uganda.Research square · 2023Article
- Prevalence and Associated Factors of Cognitive Impairment Among Stroke Survivors at Comprehensive Specialized Hospitals in Northwest Ethiopia: Multi-Centered Cross-Sectional Study.Vascular health and risk management · 2023Article
- Article
- Long-term determinants of death after stroke in Ghana: Analysis by stroke types & subtypes.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Article
- Carers' needs assessment for patients with dementia in Ghana.African journal of primary health care & family medicine · 2022Article
- New Onset Poststroke Dementia at one Year in Africans.Journal of geriatric psychiatry and neurology · 2022Observational
- Utilizing Implementation Science to Bridge Cerebrovascular Health Disparities: a Local to Global Perspective.Current neurology and neuroscience reports · 2022Review
- Educational intervention to enhance the knowledge of Ghanaian health workers on Alzheimer's disease and related dementias.African journal of primary health care & family medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectiveThere are limited data on vascular cognitive impairment (VCI) from low- and middle-income countries where the stroke burden is burgeoning. The aim of this study was to characterize the burden, determinants, and effects of VCI on health-related quality of life in sub-Saharan Africa (SSA).
methodsFrom January 2015 to February 2016, we collected information on 147 consecutive stroke survivors (>45 years) seen at a tertiary hospital in Ghana and 49 demographically matched stroke-free controls. Data collected included demographics, clinical factors, health-related quality of life, and presence of depression. Cognitive status was evaluated using a standard Vascular Neuropsychological Battery that assessed memory, executive function and mental speed, language, and visuospatial-visuoconstructive functioning. Expert VCI guideline and Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition criteria were used to classify stroke patients into no VCI, VCI but no dementia, and vascular dementia (VD).
resultsThe mean age ± standard deviation of the stroke survivors was 59.9 ± 13.7 years, of which 47.6% were women. Among the cohort, 77 out of 147 (52.3%) had no VCI, 50 of the 147 (34.0%) had VCI without dementia, and 20 of the 147 (13.6%) had VD. Three factors remained significantly associated with VCI: increasing age for each successive 10-year rise (odds ratio [OR] 1.44, 95% confidence interval [CI]: 1.03-2.02), lack of formal education (OR 5.26, 95% CI: 1.01-27.52), and worse functional disability on the modified Rankin scale (OR 2.46, 95% CI: 1.61-3.75). Patients with VD had the poorest health-related quality of life.
conclusionsHalf of the Ghanaian stroke survivors encountered in this cross-sectional study had evidence of cognitive dysfunction. Future studies in SSA will need to identify strategies to address this immense burden.
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