Evidence map›Paper›PMID 28651825›Full record

ArticleJournal of the American Academy of Dermatology2017

Prescription patterns and costs of acne/rosacea medications in Medicare patients vary by prescriber specialty.

Myron Zhang, Jonathan I Silverberg, Benjamin H Kaffenberger

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in Journal of the American Academy of Dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05296837 (ORBS), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05296837 phase4completednot on this mapstarted 2023, after this paper: background citation

ORBS: Ocular Rosacea Biome Study

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2025Enrolled46ConditionsOcular Rosacea, Antimicrobial ResistanceArmsDoxycycline 40 MG ( 20mg twice daily), Doxycycline 200 MG ( 100 mg twice daily), Placebo
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Myron ZhangDepartment of Internal Medicine, Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Jonathan I SilverbergDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Benjamin H KaffenbergerDepartment of Internal Medicine, Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address: Benjamin.Kaffenberger@osumc.edu.
The Ohio State University Wexner Medical Center · USNorthwestern University · US

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Northwestern University Patient-centered Intervention and Engagement TrainingK12HS023011 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2014 to 2018
$3.7M
AHRQ HHS K12 HS023011NCATS NIH HHS UL1 TR001070
6 · The paper itself

Abstract

backgroundPrescription patterns for acne/rosacea medications have not been described in the Medicare population, and comparisons across specialties are lacking.

objectiveTo describe the medications used for treating acne/rosacea in the Medicare population and evaluate differences in costs between specialties.

methodsA cross-sectional study was performed of the 2008 and 2010 Centers for Medicare and Medicaid Services Prescription Drug Profiles, which contains 100% of Medicare part D claims.

resultsTopical antibiotics accounted for 63% of all prescriptions. Patients ≥65 years utilized more oral tetracycline-class antibiotics and less topical retinoids. Specialists prescribed brand name drugs for the most common topical retinoids and most common topical antibiotics more frequently than family medicine/internal medicine (FM/IM) physicians by 6%-7%. Topical retinoids prescribed by specialists were, on average, $18-$20 more in total cost and $2-$3 more in patient cost than the same types of prescriptions from FM/IM physicians per 30-day supply. Specialists (60%) and IM physicians (56%) prescribed over twice the rate of branded doxycycline than FM doctors did (27%). The total and patient costs for tetracycline-class antibiotics were higher from specialists ($18 and $4 more, respectively) and IM physicians ($3 and $1 more, respectively) than they were from FM physicians. LIMITATIONS: The data might contain rare prescriptions used for conditions other than acne/rosacea, and suppression algorithms might underestimate the number of specialist brand name prescriptions.

conclusionCosts of prescriptions for acne/rosacea from specialists are higher than those from primary care physicians and could be reduced by choosing generic and less expensive options.

Indexed as

Drug CostsPractice Patterns, Physicians'Acne VulgarisAgedAged, 80 and overAnti-Bacterial AgentsCross-Sectional StudiesDrug PrescriptionsFemaleHumansMaleMedicareMedicineMiddle AgedRetinoidsRosaceaAnti-Bacterial AgentsRetinoidsacneantibioticscost of careMedicareprescription drug costsrosaceatopical retinoids

Identifiers

PMID28651825
PMCPMC5557700
OpenAlexW2636504748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.