ArticleNPJ breast cancer2017
A functionally significant SNP in TP53 and breast cancer risk in African-American women.
Open access · goldAbstract read
In one paragraph
Article in NPJ breast cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- p.Arg72Pro polymorphism of P53 and breast cancer risk: a meta-analysis of case-control studies.BMC medical genetics · 2020Pooled it
- A Personalized Therapeutic Approach for Liver Cancers Expressing the African-Centric P47S Variant of TP53.Molecular cancer research : MCR · 2026Article
- Integrative Computational Analysis ofGenes · 2026Article
- TP53 codon 47 and 72 polymorphisms show no association with HPV in Zimbabwean women living with HIV and histologically confirmed cervical and vulvar disease.Frontiers in reproductive health · 2026Article
- 3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes.Advanced biology · 2025Review
- p53-regulated non-apoptotic cell death pathways and their relevance in cancer and other diseases.Nature reviews. Molecular cell biology · 2025Review
- Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent.Cell death and differentiation · 2024Review
- CYP4B1 polymorphisms and the risk of breast cancer in Chinese women: a case-control study.BMC cancer · 2023Article
- Emerging insights into ethnic-specific TP53 germline variants.Journal of the National Cancer Institute · 2023Review
- Neither the African-Centric S47 Nor P72 Variant of TP53 Is Associated With Reduced Risk of Febrile Malaria in a Malian Cohort Study.The Journal of infectious diseases · 2023Article
- An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.Cancer discovery · 2023Article
- The African-centric P47S Variant ofCancer research communications · 2023Article
- Association ofBiomedicines · 2023Article
- Friend or Foe: Regulation, Downstream Effectors of RRAD in Cancer.Biomolecules · 2023Review
- Common activities and predictive gene signature identified for genetic hypomorphs ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
- p53 in ferroptosis regulation: the new weapon for the old guardian.Cell death and differentiation · 2022Review
- Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Identifying the link between chemical exposures and breast cancer in African American women via integrated in vitro and exposure biomarker data.Toxicology · 2021Article
- Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.Cell death and differentiation · 2021Article
- P53 regulates cellular redox state, ferroptosis and metabolism.Molecular & cellular oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 18 institutions in 2 countries.
Maureen E MurphyProgram in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA 19104 USA.
Song LiuDepartment of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY 14263 USA.
Song YaoDepartment of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263 USA.
Dezheng HuoDepartment of Public Health Sciences, University of Chicago, Chicago, , IL 60637 USA.
Qin LiuProgram in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA 19104 USA.ORCID 0000-0001-9964-580X
Sonia C DolfiDepartment of Medicine, Rutgers Robert Wood Johnson Medical School/Rutgers Cancer Institute of New Jersey, New Brunswick, , NJ 08903 USA.
Kim M HirshfieldDepartment of Medicine, Rutgers Robert Wood Johnson Medical School/Rutgers Cancer Institute of New Jersey, New Brunswick, , NJ 08903 USA.
Chi-Chen HongDepartment of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263 USA.
Qiang HuDepartment of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY 14263 USA.
Andrew F OlshanUniversity of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, , NC 27514 USA.
Temidayo O OgundiranDepartment of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Clement AdebamowoDepartment of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD 21201 USA.ORCID 0000-0002-6571-2880
Susan M DomchekDepartment of Medicine, Abramson Cancer Center, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, , PA 19104 USA.
Katherine L NathansonDepartment of Medicine, Abramson Cancer Center, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, , PA 19104 USA.
Barbara NemesureDepartment of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, NY 11794 USA.
Stefan AmbsLaboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, MD 20892 USA.
William J BlotInternational Epidemiology Institute, Rockville, MD 20850 USA.
Ye FengDepartment of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 USA.
Esther M JohnCancer Prevention Institute of California, Fremont, CA 94305 USA.
Leslie BernsteinDivision of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010 USA.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232 USA.
Jennifer J HuSylvester Comprehensive Cancer Center and Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL 33136 USA.
Regina G ZieglerEpidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 USA.
Sarah NyanteDepartment of Epidemiology, Gillings School of Global Public Health and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514 USA.
Sue A InglesDepartment of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 USA.
Michael F PressDepartment of Pathology, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 USA.
Sandra L DemingDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232 USA.
Jorge L Rodriguez-GilSylvester Comprehensive Cancer Center and Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL 33136 USA.
Christopher A HaimanDepartment of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 USA.
Olufunmilayo I OlopadeDepartment of Medicine, University of Chicago, Chicago, , IL 60637 USA.
Kathryn L LunettaDepartment of Biostatistics, Boston University, Boston, , MA 02215 USA.
Julie R PalmerSlone Epidemiology Center at Boston University, Boston, , MA 02215 USA.
Christine B AmbrosoneDepartment of Medicine, Rutgers Robert Wood Johnson Medical School/Rutgers Cancer Institute of New Jersey, New Brunswick, , NJ 08903 USA.
Roswell Park Comprehensive Cancer Center · USUniversity of Southern California · USRutgers, The State University of New Jersey · USBoston University · USNational Cancer Institute · USThe Wistar Institute · USUniversity of Miami · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USVanderbilt University · USCancer Prevention Institute of California · USChicago Department of Public Health · USCity of Hope · USInternational Epidemiology Institute · USStony Brook Medicine · USUniversity of Chicago · USUniversity of Ibadan · NGUniversity of Maryland, Baltimore · US
Funding
Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6MTRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5MTumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9MSouthern Community Cohort StudyR01CA092447 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., ZHENG, WEI · 2001 to 2015
$74.0MUNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3MTranslational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3MReproduction, Lactation and Hormonal Factors in Breast Cancer SubtypesP01CA151135 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI AMBROSONE, CHRISTINE B., OLSHAN, ANDREW · 2011 to 2017
$18.1MA Follow-up Study for Causes of Cancer in Black WomenUM1CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 2012 to 2017
$13.7MBreast Cancer Family Registry CohortUM1CA164920 · NCI · CANCER PREVENTION INSTIT OF CALIFORNIA · PI ANDRULIS, IRENE, BUYS, SAUNDRA S · 2012 to 2017
$12.7MNovel Markers for Disease Outcome in Breast CancerZIABC010887 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI AMBS, STEFAN · 2009 to 2025
$11.5MVariation in Hormone and xenobiotic metabolizing enzyme genes and breast cancerP50CA125183 · NCI · UNIVERSITY OF CHICAGO · PI COX, NANCY · 2006 to 2010
$11.3MRACE VARIABILITY IN GENOTYPIC DETERMINANTS OF BREAST CAP01CA082707 · NCI · UNIVERSITY OF PENNSYLVANIA · PI REBBECK, TIMOTHY R · 2000 to 2004
$11.0MFIC NIH HHS D43 TW009106NCI NIH HHS N01 PC067010NCI NIH HHS P01 CA082707NCI NIH HHS P01 CA151135NCI NIH HHS P30 CA010815NCI NIH HHS P30 CA016056NCI NIH HHS P30 CA072720NCI NIH HHS P50 CA125183NCI NIH HHS R01 CA089085NCI NIH HHS R01 CA092447NCI NIH HHS R01 CA102184NCI NIH HHS R01 CA135288NCI NIH HHS R01 CA142996NCI NIH HHS R01 CA201430NCI NIH HHS R25 CA057726NCI NIH HHS U01 CA161032NCI NIH HHS UM1 CA164920NCI NIH HHS UM1 CA164974NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P30 ES013508NIGMS NIH HHS T32 GM008692
Abstract
A coding region polymorphism exists in the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.