ArticleNPJ microgravity2017
Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study
Article in NPJ microgravity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Genotypic and Phenotypic Characterization of Salmonella Typhimurium Strains Isolated from Swine in the Southern Region of Brazil.Current microbiology · 2026Article
- Article
- Applying 3D cultures and high-throughput technologies to study host-pathogen interactions.Frontiers in immunology · 2025Review
- Pathogen-epithelium interactions and inflammatory responses in Salmonella Dublin infections using ileal monolayer models derived from adult bovine organoids.Scientific reports · 2024Article
- Towards using 3D cellular cultures to model the activation and diverse functions of macrophages.Biochemical Society transactions · 2023Review
- Engineering in vitro immune-competent tissue models for testing and evaluation of therapeutics.Advanced drug delivery reviews · 2022Review
- Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction BetweenFrontiers in cellular and infection microbiology · 2022Article
- The Effects of Simulated Microgravity on Macrophage Phenotype.Biomedicines · 2021Article
- Article
- Immunocompetent Human Intestinal Models in Preclinical Drug Development.Handbook of experimental pharmacology · 2021Article
- Harnessing Tissue Engineering Tools to Interrogate Host-Microbiota Crosstalk in Cancer.iScience · 2020Review
- Microbially competent 3D skin: a test system that reveals insight into host-microbe interactions and their potential toxicological impact.Archives of toxicology · 2020Article
- Comparison of two human organoid models of lung and intestinal inflammation reveals Toll-like receptor signalling activation and monocyte recruitment.Clinical & translational immunology · 2020Article
- A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni.PLoS pathogens · 2020Article
- Mammalian Cell-Based Immunoassay for Detection of Viable Bacterial Pathogens.Frontiers in microbiology · 2020Article
- A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function.Scientific reports · 2019Article
- Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics.PLoS pathogens · 2019Article
- Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580.PLoS biology · 2019Article
- ProbingFrontiers in microbiology · 2019Article
- Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age.Infection and immunity · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
Three-dimensional models of human intestinal epithelium mimic the differentiated form and function of parental tissues often not exhibited by two-dimensional monolayers and respond to
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.