Evidence map›Paper›PMID 28649608›Full record

ArticleNPJ Parkinson's disease2017

Distribution and impact on quality of life of the pain modalities assessed by the King's Parkinson's disease pain scale.

Pablo Martinez-Martin, Jose Manuel Rojo-Abuin, Alexandra Rizos, Carmen Rodriguez-Blazquez, Claudia Trenkwalder, Lauren Perkins, Anna Sauerbier, Per Odin, Angelo Antonini, Kallol Ray Chaudhuri and 1 more

Open access · goldAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Redefining Non-Motor Symptoms in Parkinson's Disease.Journal of personalized medicine · 2025
    Review
  7. Article
  8. Observational
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Musculoskeletal Pain in Parkinson's Disease.Frontiers in neurology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Pablo Martinez-MartinNational Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain.
Jose Manuel Rojo-AbuinDepartment of Statistics, Center of Human and Social Sciences, Spanish Council for Scientific Research, Madrid, Spain.
Alexandra RizosKing's College Hospital, London, UK.
Carmen Rodriguez-BlazquezNational Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain.
Claudia TrenkwalderParacelsus-Elena Hospital, Kassel, Germany.
Lauren PerkinsKing's College Hospital, London, UK.
Anna SauerbierKing's College Hospital, London, UK.
Per OdinUniversity of Lund, Lund, Sweden.
Angelo AntoniniParkinson and Movement Disorders Unit IRCCS Hospital San Camillo, Venice, Italy.
Kallol Ray ChaudhuriKing's College Hospital, London, UK.
KPPS, EUROPAR and the IPMDS Non Motor PD Study Group
King's College Hospital · GBInstituto de Salud Carlos III · ESCentro de Ciencias Humanas y Sociales · ESIstituti di Ricovero e Cura a Carattere Scientifico · ITKlinikum Bremerhaven-Reinkenheide · DEParacelsus Elena Klinik Kassel · DE

Funding

Parkinson's UK K-1210
6 · The paper itself

Abstract

In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom. The regular scores were used for the other analyses. Health-related quality of lifewas evaluated with EQ-5D-3L and PDQ-8 questionnaires. Parkinson's disease patients experienced more pain modalities than controls. In patients, Pain around joints (King's Parkinson's disease pain scale item 1) and Pain while turning in bed (item 8) were the most prevalent types of pain, whereas Burning mouth syndrome (item 11) and Pain due to grinding teeth (item 10) showed the lowest frequency. The total number of experienced pain modalities closely correlated with the PDQ-8 index, but not with other variables. For all pain types except Pain around joints (item 1) and pain related to Periodic leg movements/RLS (item 7), patients with pain had significantly worse health-related quality of life. The influence of pain, as a whole, on the health-related quality of life was not remarkable after adjustment by other variables. When the particular types of pain were considered, adjusted by sex, age, and Parkinson's disease duration, pain determinants were different for EQ-5D-3L and PDQ-8. King's Parkinson's disease pain scale allows exploring the distribution of the diverse syndromic pain occurring in Parkinson's disease and its association with health-related quality of life.

Identifiers

PMID28649608
PMCPMC5459857
OpenAlexW2593783187

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.