Evidence map›Paper›PMID 28649552›Full record

ArticleMolecular genetics and metabolism reports2015

A

Roseane Lopes da Silva-Grecco, Débora de Paula Michelatto, Carolina Rodrigues Lincoln-de-Carvalho, Pamela Pontes Henrique, Heloísa Marcelina da Cunha, Maricilda Palandi-de-Mello

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Roseane Lopes da Silva-GreccoLaboratório de Genética Molecular Humana - Centro de Biologia Molecular e Engenharia Genética (CBMEG) - Universidade Estadual de Campinas (UNICAMP), Av. Candido Rondon 400, 13083-875 Campinas, SP, Brazil.
Débora de Paula MichelattoLaboratório de Genética Molecular Humana - Centro de Biologia Molecular e Engenharia Genética (CBMEG) - Universidade Estadual de Campinas (UNICAMP), Av. Candido Rondon 400, 13083-875 Campinas, SP, Brazil.
Carolina Rodrigues Lincoln-de-CarvalhoLaboratório de Genética Molecular Humana - Centro de Biologia Molecular e Engenharia Genética (CBMEG) - Universidade Estadual de Campinas (UNICAMP), Av. Candido Rondon 400, 13083-875 Campinas, SP, Brazil.
Pamela Pontes HenriqueLaboratório de Genética Molecular Humana - Centro de Biologia Molecular e Engenharia Genética (CBMEG) - Universidade Estadual de Campinas (UNICAMP), Av. Candido Rondon 400, 13083-875 Campinas, SP, Brazil.
Heloísa Marcelina da CunhaDisciplina de Genética Humana, Departamento de Patologia, Genética e Evolução, Instituto de Ciências Biológicas e Naturais (ICBM) Universidade Federal do Triângulo Mineiro (UFTM), Praça Manoel Terra 330, 38025-180 Uberaba, MG, Brazil.
Maricilda Palandi-de-MelloLaboratório de Genética Molecular Humana - Centro de Biologia Molecular e Engenharia Genética (CBMEG) - Universidade Estadual de Campinas (UNICAMP), Av. Candido Rondon 400, 13083-875 Campinas, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital adrenal hyperplasia, one of the most frequent autosome recessive disorders, is caused by defects in steroidogenic enzymes involved in the cortisol biosynthesis. Approximately 95% of the cases are caused by abnormal function of the 21-hydroxylase enzyme. This deficiency leads to androgen excess, consequently, to virilization and rapid somatic growth with accelerated skeletal maturation. Mutations in

Indexed as

21-Hydroxylase deficiencyCongenital adrenal hyperplasiaCYP21A1 pseudo geneCYP21A2 geneIn vitro fertilizationNon-classical CAH form

Identifiers

PMID28649552
PMCPMC5471403
OpenAlexW2190465267

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.