Evidence map›Paper›PMID 28649429›Full record

ArticleNPJ systems biology and applications2017

HD Physiology Project-Japanese efforts to promote multilevel integrative systems biology and physiome research.

Kazuharu Furutani, Kunichika Tsumoto, Yoshihisa Kurachi, for HD physiology project investigators

Abstract read
In one paragraph

Article in NPJ systems biology and applications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kazuharu FurutaniDepartment of Pharmacology, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.
Kunichika TsumotoDepartment of Pharmacology, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.
Yoshihisa KurachiDepartment of Pharmacology, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.
for HD physiology project investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HD Physiology Project is a Japanese research consortium that aimed to develop methods and a computational platform in which physiological and pathological information can be described in high-level definitions across multiple scales of time and size. During the 5 years of this project, an appropriate software platform for multilevel functional simulation was developed and a whole-heart model including pharmacokinetics for the assessment of the proarrhythmic risk of drugs was developed. In this article, we outline the description and scientific strategy of this project and present the achievements and influence on multilevel integrative systems biology and physiome research.

Identifiers

PMID28649429
PMCPMC5445586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.