Evidence map›Paper›PMID 28649401›Full record

ArticleNPJ biofilms and microbiomes2016

Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients.

Jyoti Chhibber-Goel, Varsha Singhal, Debaleena Bhowmik, Rahul Vivek, Neeraj Parakh, Balram Bhargava, Amit Sharma

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 169 citations in OpenAlex.

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  12. OralJournal of oral microbiology · 2026
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jyoti Chhibber-GoelMolecular Medicine Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Varsha SinghalMolecular Medicine Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Debaleena BhowmikMolecular Medicine Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Rahul VivekMolecular Medicine Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Neeraj ParakhCardiothoracic Sciences Centre, All India Institute of Medical Sciences, New Delhi, India.
Balram BhargavaCardiothoracic Sciences Centre, All India Institute of Medical Sciences, New Delhi, India.
Amit SharmaMolecular Medicine Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
International Centre for Genetic Engineering and Biotechnology · INAll India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease is an inflammatory disorder characterized by narrowing of coronary arteries due to atherosclerotic plaque formation. To date, the accumulated epidemiological evidence supports an association between oral bacterial diseases and coronary artery disease, but has failed to prove a causal link between the two. Due to the recent surge in microbial identification and analyses techniques, a number of bacteria have been independently found in atherosclerotic plaque samples from coronary artery disease patients. In this study, we present meta-analysis from published studies that have independently investigated the presence of bacteria within atherosclerotic plaque samples in coronary artery disease patients. Data were collated from 63 studies covering 1791 patients spread over a decade. Our analysis confirms the presence of 23 oral commensal bacteria, either individually or in co-existence, within atherosclerotic plaques in patients undergoing carotid endarterectomy, catheter-based atherectomy, or similar procedures. Of these 23 bacteria, 5 (

Identifiers

PMID28649401
PMCPMC5460270
OpenAlexW2565678356

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.