Evidence map›Paper›PMID 28649247›Full record

ArticleFrontiers in immunology2017

An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8

Wei Wang, Khawar Ali Shahzad, Miaochen Li, Aifeng Zhang, Lei Zhang, Tao Xu, Xin Wan, Chuanlai Shen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Tolerogenic dendritic cells in organ transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2020
    Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wei WangDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Khawar Ali ShahzadDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Miaochen LiDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Aifeng ZhangDepartment of Pathology, Southeast University Medical School, Nanjing, China.
Lei ZhangDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Tao XuDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Xin WanDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Chuanlai ShenDepartment of Microbiology and Immunology, Southeast University Medical School, Nanjing, China.
Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selectively depleting the pathogenic T cells is a fundamental strategy for the treatment of allograft rejection and autoimmune disease since it retains the overall immune function of host. The concept of killer artificial antigen-presenting cells (KaAPCs) has been developed by co-coupling peptide-major histocompatibility complex (pMHC) multimer and anti-Fas monoclonal antibody (mAb) onto the polymeric microparticles (MPs) to induce the apoptosis of antigen-specific T cells. But little information is available about its

Indexed as

allograft rejectionalloreactive T cellsbiomimetic microparticlekiller artificial antigen-presenting cellpeptide–major histocompatibility complexpoly lactic-co-glycolic acid

Identifiers

PMID28649247
PMCPMC5465244
OpenAlexW2624074916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.