Evidence map›Paper›PMID 28649182›Full record

ArticleProceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition2016

Highly-accelerated CEST Measurements in Three Dimensions with Linear Algebraic Modeling.

Yi Zhang, Hye-Young Heo, Dong-Hoon Lee, Shanshan Jiang, Xuna Zhao, Paul Bottomley, Jinyuan Zhou

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi ZhangDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Hye-Young HeoDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Dong-Hoon LeeDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Shanshan JiangDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Xuna ZhaoDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Paul BottomleyDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Jinyuan ZhouDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.

Funding

Advanced MRI Technology in Safety & InterventionR01EB007829 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BOTTOMLEY, PAUL A · 2008 to 2017
$4.3M
Amide Proton Transfer (APT) MRI of Brain Tumors at 3T and 7TR01EB009731 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2009 to 2016
$2.9M
Academic-Industrial Partnership to Develop Clinical Brain Cancer ImagingR01CA166171 · NCI · JOHNS HOPKINS UNIVERSITY · PI VAN ZIJL, PETER CM, ZHOU, JINYUAN · 2013 to 2017
$2.4M
US-China Collaborative Research on Stroke ImagingR01NS083435 · NINDS · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2013 to 2015
$588k
NCI NIH HHS R01 CA166171NIBIB NIH HHS R01 EB007829NIBIB NIH HHS R01 EB009731NINDS NIH HHS R01 NS083435
6 · The paper itself

Abstract

CEST MRI can provide valuable molecular level information in vivo, but its translation to routine clinics is hindered by long imaging times. Regional average CEST measurements often suffice for quantitative evaluation, diagnosis, and treatment assessment, while allowing much shorter scan times. Recently, the spectroscopy with linear algebraic modeling (SLAM) method was adapted for CEST MRI in two dimensions (2D), directly obtaining compartmental-average measurements manifold faster than conventional CEST. Here, the SLAM CEST method is extended from 2D to 3D, and applied to patients with brain tumors with acceleration factors of up to 98-fold.

Identifiers

PMID28649182
PMCPMC5479684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.