Evidence map›Paper›PMID 28649084›Full record

ArticleEndocrine connections2017

Malignancy rate of focal thyroid incidentaloma detected by FDG PET-CT: results of a prospective cohort study.

Philippe Thuillier, Nathalie Roudaut, Geneviève Crouzeix, Marie Cavarec, Philippe Robin, Ronan Abgral, Véronique Kerlan, Pierre-Yves Salaun

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. The dilemma ofEndocrine · 2021
    Pooled it
  2. Focal Thyroid Incidentalomas onFrontiers in endocrinology · 2021
    Pooled it
  3. Article
  4. Definitions of Incidental [Diagnostics (Basel, Switzerland) · 2024
    Review
  5. Role of [Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  6. Article
  7. Clinical perspectives for the use of total body PET/CT.European journal of nuclear medicine and molecular imaging · 2021
    Article
  8. Characteristics of malignant thyroid lesions on [European journal of radiology open · 2021
    Article
  9. Evaluating FocalNuclear medicine and molecular imaging · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Philippe ThuillierDepartment of EndocrinologyUniversity Hospital of Brest, Brest, France philippe.thuillier@chu-brest.fr.
Nathalie RoudautDepartment of EndocrinologyUniversity Hospital of Brest, Brest, France.
Geneviève CrouzeixDepartment of EndocrinologyUniversity Hospital of Brest, Brest, France.
Marie CavarecEA GETBO 3878University Hospital of Brest, Brest, France.
Philippe RobinEA GETBO 3878University Hospital of Brest, Brest, France.
Ronan AbgralEA GETBO 3878University Hospital of Brest, Brest, France.
Véronique KerlanDepartment of EndocrinologyUniversity Hospital of Brest, Brest, France.
Pierre-Yves SalaunEA GETBO 3878University Hospital of Brest, Brest, France.
Centre Hospitalier Régional Universitaire de Brest · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the malignancy rate of focal thyroid incidentaloma (fTI) in a population of patients undergoing a 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) for a non-thyroid purpose.

designWe conducted a prospective cohort study from January 2013 to November 2014. All consecutive patients referred for a FDG PET-CT were prospectively screened. Patients with known neoplastic thyroid disease were excluded from the analysis. All patients presenting one or more fTI and who accepted to benefit from a complementary thyroid ultrasonography (US) were included and managed according to the French endocrine society consensus. Prevalence of fTI in our population and malignancy rate was assessed.

resultsDuring the inclusion period, 10,171 patients were referred for a FDG PET-CT in our center. Fifty-three patients presenting a known thyroid disease were excluded. Among the remaining 10,118 patients, 127 (1.3%) with 131 fTI were individualized. US could not be performed in 37 patients. The remaining 90 patients (92 fTI) were explored by US ± fine-needle aspiration biopsy (FNAB). US results demonstrated a nodule aspect in 80 cases of which 60 benefited from FNAB. Nineteen of 92 fTI underwent surgery with 10 malignant lesions among the 60 patients performing both US and FNAB.

conclusionThe prevalence of fTI discovered on FDG PET-CT in our population was 1.3% with 10 malignant lesions among the 60 patients performing both US and FNAB.

Indexed as

18F-fluorodeoxyglucosepositron emission tomography/computed tomographythyroid cancerthyroid incidentalomaultrasonography

Identifiers

PMID28649084
PMCPMC5551426
OpenAlexW2652254108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.