Evidence map›Paper›PMID 28648969›Full record

Trial reportContemporary clinical trials2017

A randomized controlled trial of a smoking cessation self-help intervention for dual users of tobacco cigarettes and E-cigarettes: Intervention development and research design.

Lauren R Meltzer, Vani N Simmons, Steven K Sutton, David J Drobes, Gwendolyn P Quinn, Cathy D Meade, Marina Unrod, Karen O Brandon, Paul T Harrell, Thomas Eissenberg and 2 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  4. Pooled it
  5. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2024
    Pooled it
  6. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2022
    Pooled it
  7. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2021
    Pooled it
  8. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2021
    Pooled it
  9. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  10. Print-based self-help interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Exploring the Experiences, Perceptions and Social Dynamics of Electronic Cigarette Users: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lauren R MeltzerH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States. Electronic address: Lauren.Meltzer@moffitt.org.
Vani N SimmonsH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States; University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, United States. Electronic address: Vani.Simmons@moffitt.org.
Steven K SuttonH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States; University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, United States. Electronic address: Steve.Sutton@moffitt.org.
David J DrobesH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States; University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, United States. Electronic address: David.Drobes@moffitt.org.
Gwendolyn P QuinnH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States. Electronic address: Gwen.Quinn@moffitt.org.
Cathy D MeadeH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States; University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, United States. Electronic address: Cathy.Meade@moffitt.org.
Marina UnrodH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States. Electronic address: Marina.Unrod@moffitt.org.
Karen O BrandonH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States. Electronic address: Karen.Brandon@moffitt.org.
Paul T HarrellEastern Virginia Medical School, 700 W Olney Rd, Norfolk, VA 23507, United States.
Thomas EissenbergVirginia Commonwealth University, Box 980205, Richmond, VA 23298, United States. Electronic address: teissenb@vcu.edu.
Christopher R BullenUniversity of Auckland, Auckland 1010, New Zealand.
Thomas H BrandonH. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, United States; University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, United States. Electronic address: Thomas.Brandon@moffitt.org.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-CigarettesR01DA037961 · NIDA · H. LEE MOFFITT CANCER CTR & RES INST · PI BRANDON, THOMAS H · 2015 to 2019
$3.7M
NCI NIH HHS P30 CA076292NIDA NIH HHS R01 DA037961
6 · The paper itself

Abstract

Electronic Nicotine Delivery Systems, also called electronic cigarettes or e-cigarettes, have been available for over a decade and use has been increasing dramatically. The primary reported reasons for use are to aid smoking cessation or reduction, yet a significant proportion appear to be long-term users of both products ("dual users"). Dual users may be motivated to quit smoking and might benefit from a behavioral intervention for smoking cessation. This paper describes the intervention development, as well as the design, methods, and data analysis plans for an ongoing randomized controlled trial (RCT). Formative research and learner verification were conducted to create a usable, understandable, and acceptable self-help intervention targeting dual users. The efficacy is being tested in an RCT with current dual users (N=2900) recruited nationally and randomized to one of three conditions. The Assessment Only (ASSESS) group only completes assessments. The Generic Self-Help (GENERIC) group receives non-targeted smoking cessation booklets and supplemental materials sent monthly over 18months. The e-cigarette Targeted Self-Help (eTARGET) group receives the newly developed intervention (targeted booklets and supplemental materials) sent over the same period. All participants complete self-report surveys every 3months over 2years. The primary study outcome is self-reported 7-day point prevalence abstinence. Cost-effectiveness metrics for the GENERIC and eTARGET interventions will also be calculated.

Indexed as

Electronic Nicotine Delivery SystemsCost-Benefit AnalysisHealth BehaviorHumansPatient Education as TopicSelf CareSmoking CessationE-cigarettes, dual-useRandomized controlled trialSelf-helpSmoking

Identifiers

PMID28648969
PMCPMC5559662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.