Evidence map›Paper›PMID 28648897›Full record

ArticleStem cell reports2017

Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells.

Arantxa Cebrián-Silla, Clara Alfaro-Cervelló, Vicente Herranz-Pérez, Naoko Kaneko, Dae Hwi Park, Kazunobu Sawamoto, Arturo Alvarez-Buylla, Daniel A Lim, José Manuel García-Verdugo

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Arantxa Cebrián-SillaLaboratory of Comparative Neurobiology, Institute Cavanilles, University of Valencia, CIBERNED, 46980 Valencia, Spain.
Clara Alfaro-CervellóServicio de Anatomía Patológica, Hospital Clínico Universitario de Valencia, 46010 Valencia, Spain.
Vicente Herranz-PérezLaboratory of Comparative Neurobiology, Institute Cavanilles, University of Valencia, CIBERNED, 46980 Valencia, Spain; Predepartamental Unit of Medicine, Faculty of Health Sciences, Universitat Jaume I, 12071 Castelló de la Plana, Spain.
Naoko KanekoDepartment of Developmental and Regenerative Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Dae Hwi ParkDepartment of Neurological Surgery, The Eli and Edythe Broad Center of Regeneration Medicine, Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA.
Kazunobu SawamotoDepartment of Developmental and Regenerative Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan; Division of Neural Development and Regeneration, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan.
Arturo Alvarez-BuyllaDepartment of Neurological Surgery, The Eli and Edythe Broad Center of Regeneration Medicine, Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA.
Daniel A LimDepartment of Neurological Surgery, The Eli and Edythe Broad Center of Regeneration Medicine, Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, CA 94143, USA.
José Manuel García-VerdugoLaboratory of Comparative Neurobiology, Institute Cavanilles, University of Valencia, CIBERNED, 46980 Valencia, Spain; Multiple Sclerosis and Neuroregeneration Mixed Unit, IIS Hospital La Fe, 46026 Valencia, Spain. Electronic address: j.manuel.garcia@uv.es.
Nagoya City University · JPUniversitat de València · ESUniversity of California, San Francisco · USHospital Clínico Universitario de Valencia · ESNeurological Surgery · USUniversitat Jaume I · ES

Funding

BLRD VA I01 BX000252
6 · The paper itself

Abstract

Neural stem cells (B1 astrocytes; NSCs) in the adult ventricular-subventricular-zone (V-SVZ) originate in the embryo. Surprisingly, recent work has shown that B1 cells remain largely quiescent. They are reactivated postnatally to function as primary progenitors for neurons destined for the olfactory bulb and some corpus callosum oligodendrocytes. The cellular and molecular properties of quiescent B1 cells remain unknown. Here we found that a subpopulation of B1 cells has a unique nuclear envelope invagination specialization similar to envelope-limited chromatin sheets (ELCS), reported in certain lymphocytes and some cancer cells. Using molecular markers, [

Indexed as

Adult Stem CellsAnimalsAstrocytesCell CycleCells, CulturedChromatinLateral VentriclesMiceNeural Stem CellsNuclear EnvelopeChromatinneural stem cellsnuclear ELCSnuclear envelope invaginationsquiescenceV-SVZ

Identifiers

PMID28648897
PMCPMC5511107
OpenAlexW2648125055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.