Evidence map›Paper›PMID 28648781›Full record

ArticleMolecular cell2017

PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response.

Elisa Ferrari, Christopher Bruhn, Marta Peretti, Corinne Cassani, Walter Vincenzo Carotenuto, Mohamed Elgendy, Ghadeer Shubassi, Chiara Lucca, Rodrigo Bermejo, Mario Varasi and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

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  10. Experimental evolution ofbioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Elisa FerrariFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Christopher BruhnFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Marta PerettiFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Corinne CassaniUniversità degli Studi di Milano-Bicocca, 20126 Milan, Italy.
Walter Vincenzo CarotenutoFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Mohamed ElgendyIstituto Europeo di Oncologia, Via Adamello 16, 20139 Milan, Italy.
Ghadeer ShubassiFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Chiara LuccaFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Rodrigo BermejoCentro de Investigaciones Biológicas (CIB-CSIC), 28040 Madrid, Spain.
Mario VarasiFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.
Saverio MinucciIstituto Europeo di Oncologia, Via Adamello 16, 20139 Milan, Italy; Università degli Studi di Milano, 20133 Milan, Italy.
Maria Pia LongheseUniversità degli Studi di Milano-Bicocca, 20126 Milan, Italy.
Marco FoianiFondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy; Università degli Studi di Milano, 20133 Milan, Italy. Electronic address: marco.foiani@ifom.eu.
IFOM · ITUniversity of Milan · ITUniversity of Milano-Bicocca · ITCentro de Investigaciones Biológicas Margarita Salas · ESEuropean Institute of Oncology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mec1

Indexed as

DNA DamageDNA RepairEnergy MetabolismGenome, FungalGenomic InstabilityAdaptor Proteins, Signal TransducingCeramidesCytochrome-B(5) ReductaseDNA, FungalEnzyme ActivationGene Expression Regulation, FungalIntracellular Signaling Peptides and ProteinsMetabolomicsMutationProtein Kinase InhibitorsProtein MethyltransferasesAdaptor Proteins, Signal TransducingCeramidesCytochrome-B(5) ReductaseDNA, FungalIntracellular Signaling Peptides and ProteinsMEC1 protein, S cerevisiaePpm1 protein, S cerevisiaeProtein Kinase InhibitorsProtein MethyltransferasesProtein Phosphatase 2Protein Serine-Threonine KinasesSaccharomyces cerevisiae ProteinsSirolimusTAP42 protein, S cerevisiaeTORC1 protein complex, S cerevisiaeTranscription FactorsDNA damage responsegenome stabilityIrc21Mec1-ATRmetabolismprotein phosphatase PP2ARad53TORC1

Identifiers

PMID28648781
PMCPMC5526790
OpenAlexW2652333723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.