Evidence map›Paper›PMID 28647787›Full record

ArticleJournal of assisted reproduction and genetics2017

Using stem cell oxygen physiology to optimize blastocyst culture while minimizing hypoxic stress.

Alan Bolnick, Awoniyi O Awonuga, Yu Yang, Mohammed Abdulhasan, Yufen Xie, Sichang Zhou, Elizabeth E Puscheck, Daniel A Rappolee

Open access · bronzeAbstract readComment
In one paragraph

Article in Journal of assisted reproduction and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
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  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Alan BolnickCS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Awoniyi O AwonugaCS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Yu YangCS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Mohammed AbdulhasanCS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Yufen XieFertility and Surgical Associates of California, Thousand Oaks, CA, 91361, USA.
Sichang ZhouUniversity of Michigan Medical School, Ann Arbor, MI, 48109, USA.
Elizabeth E PuscheckCS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Daniel A RappoleeCS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA. drappole@med.wayne.edu.
Wayne State University · USUniversity of Michigan–Ann Arbor · USUniversity Surgical Associates · USWomen & Children's Hospital of Buffalo · US

Funding

AMP-activated protein kinase management will improve oocyte cryopreservationR03HD061431 · NICHD · WAYNE STATE UNIVERSITY · PI RAPPOLEE, DANIEL ALLEN · 2009 to 2010
$152k
NICHD NIH HHS R03 HD061431
6 · The paper itself

Abstract

This review is a response to the Fellows Forum on testing 2% oxygen for best culture of human blastocysts (J Ass Reprod Gen 34:303-8, 1; J Ass Reprod Gen 34:309-14, 2) prior to embryo transfer. It is a general analysis in support of the position that an understanding of stem cell physiology and responses to oxygen are necessary for optimization of blastocyst culture in IVF and to enhance reproductive success in fertile women.

Indexed as

InfertilityOxygenBlastocystCell Physiological PhenomenaFellowships and ScholarshipsFemaleHumansStem CellsOxygenBlastocystHypoxic stressIVFOxygen optimizationStem cells

Identifiers

PMID28647787
PMCPMC5633568
OpenAlexW2704752719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.