Evidence map›Paper›PMID 28647690›Full record

Observational studyJournal of the American Heart Association2017

Acute Kidney Injury After Primary Angioplasty: Is Contrast-Induced Nephropathy the Culprit?

Oren Caspi, Manhal Habib, Yuval Cohen, Arthur Kerner, Ariel Roguin, Eitan Abergel, Monther Boulos, Michael R Kapeliovich, Rafael Beyar, Eugenia Nikolsky and 1 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04382313 (Effect of Hydration Guided by Vigileo on the Prevention of Contrast Induced Nephropathy After Emergency PCI for Patients With Acute Myocardial Infarction), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04382313 nacompletednot on this mapstarted 2020, after this paper: background citation

Effect of Hydration Guided by Vigileo on the Prevention of Contrast Induced Nephropathy After Emergency PCI for Patients With Acute Myocardial Infarction

TypeinterventionalSponsorChinese PLA General HospitalRan2020 to 2022Enrolled344ConditionsMyocardial Infarction, Contrast-induced NephropathyArmsthe adequate hydration group guided by Vigileo
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  6. Review
  7. Interleukin-10 attenuates renal injury after myocardial infarction in diabetes.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Oren CaspiDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Manhal HabibDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Yuval CohenDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Arthur KernerDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Ariel RoguinDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Eitan AbergelDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Monther BoulosDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Michael R KapeliovichDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Rafael BeyarDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Eugenia NikolskyDepartment of Cardiology, Rambam Medical Center, Haifa, Israel.
Doron AronsonDepartment of Cardiology, Rambam Medical Center, Haifa, Israel daronson@technion.edu.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) following primary percutaneous coronary intervention (pPCI) is frequently interpreted as contrast-induced AKI but may result from other insults. We aimed to determine the causal association of contrast material exposure and the incidence of AKI following pPCI using a control group of propensity score-matched patients with ST-segment-elevation myocardial infarction who were not exposed to contrast material. METHODS AND

resultsWe studied 2025 patients with ST-segment-elevation myocardial infarction who underwent pPCI and 1025 patients receiving fibrinolysis or no reperfusion who were not exposed to contrast material during the first 72 hours of hospital stay (control group). AKI was defined as creatinine of ≥0.5 mg/dL or >25% rise within 72 hours. AKI rates were similar in the pPCI and control groups (10.3% versus 12.1%, respectively;

conclusionsThe development of AKI in patients with ST-segment-elevation myocardial infarction undergoing pPCI is mainly related to older age, baseline estimated glomerular filtration rate, heart failure, and hemodynamic instability. Risk for AKI is similar among ST-segment-elevation myocardial infarction patients with and without contrast material exposure.

Indexed as

Acute Kidney InjuryAgedAge FactorsCase-Control StudiesChi-Square DistributionContrast MediaDatabases, FactualDisease-Free SurvivalFemaleGlomerular Filtration RateHeart FailureHemodynamicsHumansIncidenceIsraelKaplan-Meier EstimateContrast Mediacontrast‐induced nephropathycontrast mediamyocardial infarctionprimary percutaneous coronary intervention

Identifiers

PMID28647690
PMCPMC5669180

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.