ArticleJournal of the American Heart Association2017
Associations of Cigarette Smoking With Subclinical Inflammation and Atherosclerosis: ELSA-Brasil (The Brazilian Longitudinal Study of Adult Health).
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 102 citations in OpenAlex.
- Influence of cigarette smoking on cardio-inflammatory biomarkers among healthy individuals or cardiopulmonary disorder patients: systematic review and meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- Association between cigarette smoking and carotid intima-media thickness among young Saudi adults: a cross-sectional ultrasonographic study.BMC cardiovascular disorders · 2026Article
- Associations of cigarette smoking with coronary artery and extra-coronary calcification in older adults: The Atherosclerosis Risk in Communities study.Atherosclerosis · 2026Article
- Association between dietary inflammatory index and cardiovascular‑kidney‑metabolic syndrome: evidence from NHANES 1999-2018.BMC cardiovascular disorders · 2025Article
- Article
- Association Between Cigarette Smoking and Subclinical Markers of Cardiovascular Harm.Journal of the American College of Cardiology · 2025Article
- Prospective Associations of Dietary Antioxidant Vitamin Intake and 8-Year Risk of Elevated SerumNutrients · 2025Article
- Aging and "Age-Related" Diseases - What Is the Relation?Aging and disease · 2024Review
- Associations of psychological factors with atherosclerosis and cardiovascular health in middle-age: the population-based Swedish CArdioPulmonary bioImage study (SCAPIS).BMC public health · 2024Article
- Association between smoking status and subclinical coronary atherosclerosis in asymptomatic Korean individuals.Epidemiology and health · 2024Article
- Association of cardiovascular risk factors and intraplaque neovascularization in symptomatic carotid plaque.Frontiers in neurology · 2024Article
- Effect of Aerobic Exercise on Arterial Stiffness in Individuals with Different Smoking Statuses.International journal of sports medicine · 2023Article
- Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-Tobacco working group rationale, design, and methodology.Tobacco induced diseases · 2023Article
- Statin Use and Risk of Diabetes by Subclinical Atherosclerosis Burden (from a Multi-Ethnic Study of Atherosclerosis Report).The American journal of cardiology · 2022 · on this mapObservational
- Serum LDL-C/HDL-C ratio and the risk of carotid plaques: a longitudinal study.BMC cardiovascular disorders · 2022Article
- Biomarkers of Exposure and Potential Harm in Exclusive Users of Nicotine Pouches and Current, Former, and Never Smokers: Protocol for a Cross-sectional Clinical Study.JMIR research protocols · 2022Article
- Article
- Effect of high-sensitivity C-reactive protein on the relationship between haemoglobin A1c and cardiovascular events in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a cohort study.Cardiovascular diagnosis and therapy · 2022Article
- Review
- Determinants of Incident Atherosclerotic Cardiovascular Disease Events Among Those With Absent Coronary Artery Calcium: Multi-Ethnic Study of Atherosclerosis.Circulation · 2022Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundThere is a need to identify sensitive biomarkers of early tobacco-related cardiovascular disease. We examined the association of smoking status, burden, time since quitting, and intensity, with markers of inflammation and subclinical atherosclerosis. METHODS AND
resultsWe studied 14 103 participants without clinical cardiovascular disease in ELSA-Brasil (Brazilian Longitudinal Study of Adult Health). We evaluated baseline cross-sectional associations between smoking parameters and inflammation (high-sensitivity C-reactive protein [hsCRP]) and measures of subclinical atherosclerosis (carotid intima-media thickness, ankle-brachial index, and coronary artery calcium [CAC]). The cohort included 1844 current smokers, 4121 former smokers, and 8138 never smokers. Mean age was 51.7±8.9 years; 44.8% were male. After multivariable adjustment, compared with never smokers, current smokers had significantly higher levels of hsCRP (β=0.24, 0.19-0.29 mg/L;
conclusionsStrong associations were observed between smoking status, burden, and intensity with inflammation (hsCRP) and subclinical atherosclerosis (carotid intima-media thickness, ankle-brachial index, CAC). These markers of early cardiovascular disease injury may be used for the further study and regulation of traditional and novel tobacco products.
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