Evidence map›Paper›PMID 28647513›Full record

Observational studyEnvironmental research2017

Respiratory syncytial virus bronchiolitis, weather conditions and air pollution in an Italian urban area: An observational study.

Raffaella Nenna, Melania Evangelisti, Antonella Frassanito, Carolina Scagnolari, Alessandra Pierangeli, Guido Antonelli, Ambra Nicolai, Serena Arima, Corrado Moretti, Paola Papoff and 2 more

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 6 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 6 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Impact of air pollution on COVID-19 severity: a systematic review of underlying biological mechanisms.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  5. Air pollution and hospitalization risk in infants with bronchiolitis: A systematic review and meta-analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Pooled it
  6. The Effect of High and Low Ambient Temperature on Infant Health: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  7. Observational
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  13. Review
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  15. Climate Change and the Future of Allergies and Asthma.Current allergy and asthma reports · 2025
    Review
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Raffaella NennaDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University, Rome, Italy.
Melania EvangelistiPediatric Sleep Disease Center, Child Neurology, NESMOS Department, "Sapienza" University of Rome, S. Andrea Hospital, Rome, Italy.
Antonella FrassanitoDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University, Rome, Italy.
Carolina ScagnolariDepartment of Pediatrics and Virology Laboratory, Department of Molecular Medicine, "Sapienza" University, Rome, Italy.
Alessandra PierangeliDepartment of Pediatrics and Virology Laboratory, Department of Molecular Medicine, "Sapienza" University, Rome, Italy.
Guido AntonelliDepartment of Pediatrics and Virology Laboratory, Department of Molecular Medicine, "Sapienza" University, Rome, Italy.
Ambra NicolaiDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University, Rome, Italy.
Serena ArimaDepartment of Methods and Models in Economics, the Territory and Finance, "Sapienza" University, Rome, Italy.
Corrado MorettiDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University, Rome, Italy.
Paola PapoffDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University, Rome, Italy.
Maria Pia VillaPediatric Sleep Disease Center, Child Neurology, NESMOS Department, "Sapienza" University of Rome, S. Andrea Hospital, Rome, Italy.
Fabio MidullaDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University, Rome, Italy. Electronic address: midulla@uniroma1.it.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study we sought to evaluate the association between viral bronchiolitis, weather conditions, and air pollution in an urban area in Italy.

methodsWe included infants hospitalized for acute bronchiolitis from 2004 to 2014. All infants underwent a nasal washing for virus detection. A regional agency network collected meteorological data (mean temperature, relative humidity and wind velocity) and the following air pollutants: sulfur dioxide, nitrogen oxide, carbon monoxide, ozone, benzene and suspended particulate matter measuring less than 10µm (PM

resultsOf the 723 nasal washings from the infants enrolled, 266 (68%) contained RSV, 63 (16.1%) rhinovirus, 26 (6.6%) human bocavirus, 20 (5.1%) human metapneumovirus, and 16 (2.2%) other viruses. The number of RSV-positive infants correlated negatively with temperature (p < 0.001), and positively with relative humidity (p < 0.001). Air pollutant concentrations differed significantly during the peak RSV months and the other months. Benzene concentration was independently associated with RSV incidence (p = 0.0124).

conclusionsSeasonal weather conditions and concentration of air pollutants seem to influence RSV-related bronchiolitis epidemics in an Italian urban area.

Indexed as

Environmental MonitoringWeatherAir PollutantsAir PollutionBronchiolitisCitiesFemaleHumansIncidenceInfantInfant, NewbornItalyMaleProspective StudiesRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAir PollutantsAir pollutionBronchiolitisInfantsMeteorological dataRespiratory syncytial virus

Identifiers

PMID28647513
PMCPMC7125886
OpenAlexW2725563785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.