Evidence map›Paper›PMID 28646891›Full record

ArticleParasites & vectors2017

Absence of Batf3 results in reduced liver pathology in mice infected with Schistosoma japonicum.

Lin Chen, Donghui Zhang, Wenyue Zhang, Yuxiao Zhu, Min Hou, Bingya Yang, Zhipeng Xu, Minjun Ji, Guanling Wu

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lin ChenDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China. linchen@njmu.edu.cn.
Donghui ZhangDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Wenyue ZhangDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Yuxiao ZhuDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Min HouDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Bingya YangDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Zhipeng XuDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Minjun JiDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Guanling WuDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe involvement of CD8

resultsIn this study, we showed that the absence of Batf3 alleviated liver damage in Batf3

conclusionsOur study provides evidence that Batf3 is associated with the immunoregulation of the liver granuloma formation, which may confer a new options for schistosomiasis treatment.

Indexed as

AnimalsBasic-Leucine Zipper Transcription FactorsCD8-Positive T-LymphocytesDendritic CellsFemaleFlow CytometryGranulomaLiverLiver DiseasesMiceMice, Inbred C57BLReal-Time Polymerase Chain ReactionRepressor ProteinsSchistosomiasis japonicaSnailsSpleenBasic-Leucine Zipper Transcription FactorsRepressor ProteinsSNFT protein, mouseBatf3CD8+T cellsCD8α+Dendritic cellsHelminthSchistosoma japonicum

Identifiers

PMID28646891
PMCPMC5483257
OpenAlexW2696547352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.