ArticleBiomedical engineering online2017
A clinical utility assessment of the automatic measurement method of the quality of Meibomian glands.
Article in Biomedical engineering online, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- A Comprehensive Review Comparing Artificial Intelligence and Clinical Diagnostic Approaches for Dry Eye Disease.Diagnostics (Basel, Switzerland) · 2025Review
- AI driven quantitative analysis of meibomian glands in children and adolescents: a benchmark dataset study.Eye and vision (London, England) · 2025Article
- Global research of artificial intelligence in eyelid diseases: A bibliometric analysis.Heliyon · 2024Article
- The Effects of Soft Contact Lens Wear on The Tear Film and Meibomian Gland Drop-Out and Visibility.Life (Basel, Switzerland) · 2022Article
- Is histogram manipulation always beneficial when trying to improve model performance across devices? Experiments using a Meibomian gland segmentation model.Frontiers in cell and developmental biology · 2022Article
- Meibomian glands visibility assessment through a new quantitative method.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Fluorescent contact lens for continuous non-invasive measurements of sodium and chloride ion concentrations in tears.Analytical biochemistry · 2020Article
- Visible Meibomian Gland Structure Increases After Vectored Thermal Pulsation Treatment in Dry Eye Disease Patients with Meibomian Gland Dysfunction.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- A Novel Automated Approach for Infrared-Based Assessment of Meibomian Gland Morphology.Translational vision science & technology · 2019Article
- Improving accuracy of corneal power measurement with partial coherence interferometry after corneal refractive surgery using a multivariate polynomial approach.Biomedical engineering online · 2018Article
- Topical review of the relationship between contact lens wear and meibomian gland dysfunction.Journal of optometryReview
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMeibomian gland dysfunction (MGD) is one of the most common diseases observed in clinics and is the leading cause of evaporative dry eye. Today, diagnostics of MGD is not fully automatic yet and is based on a qualitative assessment made by an ophthalmologist. Therefore, an automatic analysis method was developed to assess MGD quantiatively. MATERIALS: The analysis made use of 228 images of 57 patients recorded by OCULUS Keratograph
methodsThe presented method of analysis is a new, developed method enabling an automatic, reproducible and quantitative assessment of Meibomian glands. The analysis relates to employing the methods of analysis and image processing. The analysis was conducted in the Matlab environment Version 7.11.0.584, R2010b, Java VM Version: Java 1.6.0_17-b04 with Sun Microsystems Inc. with toolboxes: Statistical, Signal Processing and Image Processing.
resultsThe presented, new method of analysis of Meibomian glands is fully automatic, does not require operator's intervention, allows obtaining reproducible results and enables a quantitative assessment of Meibomian glands. Compared to the other known methods, particularly with the method described in literature it allows obtaining better sensitivity (98%) and specificity (100%) results by 2%.
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