Evidence map›Paper›PMID 28646445›Full record

ReviewCurrent cardiology reports2017

Update on Neurocritical Care of Stroke.

Jason Siegel, Michael A Pizzi, J Brent Peel, David Alejos, Nnenne Mbabuike, Benjamin L Brown, David Hodge, W David Freeman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Non-invasive treatment with near-infrared light: A novel mechanisms-based strategy that evokes sustained reduction in brain injury after stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jason SiegelDepartment of Neurology, Mayo Clinic, 4500 San Pablo Road,, Jacksonville, FL, 32224, USA. Siegel.jason@mayo.edu.
Michael A PizziDepartment of Neurology, Mayo Clinic, 4500 San Pablo Road,, Jacksonville, FL, 32224, USA.
J Brent PeelDepartment of Neurology, Mayo Clinic, 4500 San Pablo Road,, Jacksonville, FL, 32224, USA.
David AlejosDepartment of Critical Care Medicine, Mayo Clinic, Jacksonville, FL, USA.
Nnenne MbabuikeDepartment of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
Benjamin L BrownDepartment of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
David HodgeDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA.
W David FreemanDepartment of Neurology, Mayo Clinic, 4500 San Pablo Road,, Jacksonville, FL, 32224, USA.
Mayo Clinic in Florida · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review will highlight the recent advancements in acute ischemic stroke diagnosis and treatment, with special attention to new features and recommendations of stroke care in the neurocritical care unit. RECENT

findingsNew studies suggest that pre-hospital treatment of stroke with mobile stroke units and telestroke technology may lead to earlier stroke therapy with intravenous tissue plasminogen activator (tPA), and recent studies show tPA can be given in previously contraindicated situations. More rapid automated CT perfusion and angiography may demonstrate a vascular penumbra for neuroendovascular intervention. Further, the greatest advance in acute stroke treatment since 2014 is the demonstration that neuroendovascular catheter-based thrombectomy with stent retrievers recanalizing intracranial large vessel occlusion (LVO) improves both recanalization and long-term outcomes in several trials. Hemorrhagic transformation and severe large infarct cerebral edema remain serious post-stroke challenges, with new guidelines describing who and when patients should get medical or surgical intervention. The adage "time is brain" directs the most evidence-based approach for rapid stroke diagnosis for tPA eligible and LVO recanalization using an orchestrated team approach. The neurocritical care unit is the appropriate location to optimize stroke outcomes for the most severely affected stroke patients.

Indexed as

Acute DiseaseBrainBrain IschemiaFibrinolytic AgentsHumansStentsStrokeTelemedicineThrombectomyTime-to-TreatmentTissue Plasminogen ActivatorFibrinolytic AgentsTissue Plasminogen ActivatorAcute ischemic strokeEdemaHemorrhageNeuroimagingThrombectomytPA

Identifiers

PMID28646445
OpenAlexW2721242840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.