Evidence map›Paper›PMID 28646437›Full record

ArticleEnvironmental monitoring and assessment2017

Cytotoxic and genotoxic effects of silver nanoparticle/carboxymethyl cellulose on Allium cepa.

Aline A Becaro, Maria Célia Siqueira, Fernanda C Puti, Marcia Regina de Moura, Daniel S Correa, José Manoel Marconcini, Luiz H C Mattoso, Marcos David Ferreira

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Environmental monitoring and assessment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Argovit™ Silver Nanoparticles Effects onNanomaterials (Basel, Switzerland) · 2020
    Article
  10. Article
  11. Article
  12. Recent Developments in Food Packaging Based on Nanomaterials.Nanomaterials (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Aline A BecaroPrograma de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
Maria Célia SiqueiraLaboratório Nacional de Nanotecnologia para o Agronegócio (LNNA), EMBRAPA Instrumentação, São Carlos, SP, 13560-970, Brazil.
Fernanda C PutiPrograma de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
Marcia Regina de MouraDepartamento de Física e Química, UNESP, Ilha Solteira, SP, 15385-000, Brazil.
Daniel S CorreaPrograma de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
José Manoel MarconciniLaboratório Nacional de Nanotecnologia para o Agronegócio (LNNA), EMBRAPA Instrumentação, São Carlos, SP, 13560-970, Brazil.
Luiz H C MattosoLaboratório Nacional de Nanotecnologia para o Agronegócio (LNNA), EMBRAPA Instrumentação, São Carlos, SP, 13560-970, Brazil.
Marcos David FerreiraPrograma de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil. marcos.david@embrapa.br.
Laboratório Nacional de NanotecnologiaBrazilian Agricultural Research Corporation · BRUniversidade Federal de São Carlos · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several mutagenic agents may be present in substances released in the environment, which may cause serious environmental impacts. Among these substances, there is a special concern regarding the widespread use of silver nanoparticles (AgNP) in several products due to their widely known bactericidal properties, including in the medical field and the food industry (e.g., active packaging). The assessment of the effects of AgNP released in the environment, having different concentrations, sizes, and being associated or not to other types of materials, including polymers, is therefore essential. In this research, the objective was to evaluate the genotoxic and cytotoxic effects of AgNP (size range between 2 and 8 nm) on root meristematic cells of Allium cepa (A. cepa). Tests were carried out in the presence of colloidal solution of AgNP and AgNP mixed with carboxymethylcellulose (CMC), using distinct concentrations of AgNP. As a result, when compared to control samples, AgNP induced a mitotic index decrease and an increase of chromosomal aberration number for two studied concentrations. When AgNP was in the presence of CMC, no cytotoxic potential was verified, but only the genotoxic potential for AgNP dispersion having concentration of 12.4 ppm.

Indexed as

AlliumCarboxymethylcellulose SodiumChromosome AberrationsDNA DamageEnvironmental MonitoringMetal NanoparticlesMutagensNanoparticlesOnionsPlant RootsSilverCarboxymethylcellulose SodiumMutagensSilverAllium cepaCarboxymethylcelluloseChromosomal aberrationMitotic testSilver nanoparticles

Identifiers

PMID28646437
OpenAlexW2678389288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.