Evidence map›Paper›PMID 28646359›Full record

ReviewJournal of medical toxicology : official journal of the American College of Medical Toxicology2017

Music as an Adjunct to Opioid-Based Analgesia.

Peter R Chai, Stephanie Carreiro, Megan L Ranney, Ketki Karanam, Marko Ahtisaari, Robert Edwards, Kristin L Schreiber, Lubabah Ben-Ghaly, Timothy B Erickson, Edward W Boyer

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06948890 (Effect of Music on Cue Reactivity for Patients With Opioid Use Disorder), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06948890 nacompletednot on this mapstarted 2025, after this paper: background citation

Effect of Music on Cue Reactivity for Patients With Opioid Use Disorder

TypeinterventionalSponsorBrigham and Women's HospitalRan2025 to 2026Enrolled28ConditionsOpioid Use DisorderArmsMusic intervention, Silence
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Emotional responses to favorite and relaxing music predict music-induced hypoalgesia.Frontiers in pain research (Lausanne, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peter R ChaiDivision of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02114, USA. pchai@bwh.harvard.edu.
Stephanie CarreiroDivision of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA, USA.
Megan L RanneyDepartment of Emergency Medicine, Rhode Island Hospital, Alpert Medical School, Brown University, 55 Claverick St, Providence, RI, 02903, USA.
Ketki KaranamThe Sync Project, Inc, 186 South Street, Boston, MA, 02111, USA.
Marko AhtisaariThe Sync Project, Inc, 186 South Street, Boston, MA, 02111, USA.
Robert EdwardsDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis St, Boston, MA, 02114, USA.
Kristin L SchreiberDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis St, Boston, MA, 02114, USA.
Lubabah Ben-GhalyDivision of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02114, USA.
Timothy B EricksonDivision of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02114, USA.
Edward W BoyerDivision of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02114, USA.

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
University of Massachusetts Center for Clinical and Translational ScienceKL2TR001455 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2015 to 2024
$5.0M
Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse ResearchK24DA037109 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOYER, EDWARD W · 2014 to 2025
$1.9M
National Institute on Drug Abuse 1K24DA037109National Institutes of Health KL2 TR001455NCATS NIH HHS KL2 TR001455NCATS NIH HHS UL1 TR001453NIDA NIH HHS K24 DA037109
6 · The paper itself

Abstract

Epidemic increases in opioid use in the USA and globally highlight the need for effective adjunctive therapies to opioid-based analgesia. Given the shortcomings of behavioral adjuncts to opioid-based pain treatment, an urgent need exists for pain-related behavioral interventions that resonate with broad patient populations, can be delivered confidentially in any environment, and can incorporate new content automatically. Understanding the potential for automated behavioral therapies like music therapy in modulating the experience of pain may unlock methods to transition patients to lower doses of pharmacologic therapy or provide alternatives to opioids during acute exacerbations of pain. This manuscript describes the neurologic mechanism of action, theoretical basis, and potential applications of personalized music as a smartphone-based mHealth intervention for acute and chronic pain management.

Indexed as

Acute PainAffectAnalgesics, OpioidChronic PainCombined Modality TherapyHumansMobile ApplicationsMusic TherapyOpioid-Related DisordersPain ManagementPain MeasurementPain PerceptionPain ThresholdPatient Care TeamSmartphoneTelemedicineAnalgesics, OpioidBehavioral medicinemHealthMusicOpioidsPain

Identifiers

PMID28646359
PMCPMC5570730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.