ArticleEuropean journal of applied physiology2017
T-regulatory cells exhibit a biphasic response to prolonged endurance exercise in humans.
Article in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Acute hyperketonaemia alters T-cell-related cytokine gene expression within stimulated peripheral blood mononuclear cells following prolonged exercise.European journal of applied physiology · 2020Trial
- Exploring the functional role of palmitoylation genes in clear cell renal cell carcinoma and their impact on tumor microenvironment.BMC genomic data · 2026Article
- An ultra-endurance event leads to changes in circulating regulatory T-cells, CD4+ naïve and CD8+ effector memory T-cells in the 48 h post-race recovery period.European journal of applied physiology · 2025Article
- Physical activity and glioblastoma: a paradigm shift in neuro-oncology therapy.Frontiers in oncology · 2025Review
- Immunological regulation of skeletal muscle adaptation to exercise.Cell metabolism · 2024Review
- Immune consequences of exercise in hypoxia: A narrative review.Journal of sport and health science · 2024Review
- Regulatory T cells shield muscle mitochondria from interferon-γ-mediated damage to promote the beneficial effects of exercise.Science immunology · 2023Article
- Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity?Cancers · 2023Review
- Single-cell sequencing of immune cells after marathon and symptom-limited cardiopulmonary exercise.iScience · 2023Article
- Microbial bowel infections-induced biochemical and biological abnormalities and their effects on young Egyptian swimmers.Scientific reports · 2023Article
- The Impact of Exercise on Immunity, Metabolism, and Atherosclerosis.International journal of molecular sciences · 2023Review
- The skeleton in a physical world.Experimental biology and medicine (Maywood, N.J.) · 2022Review
- Development and Validation of Recreational Sport Well-Being Scale.International journal of environmental research and public health · 2022Article
- Evidence of immunometabolic dysregulation and airway dysbiosis in athletes susceptible to respiratory illness.EBioMedicine · 2022Article
- Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- The Effect of Physical Training on Peripheral Blood Mononuclear Cell Ex Vivo Proliferation, Differentiation, Activity, and Reactive Oxygen Species Production in Racehorses.Antioxidants (Basel, Switzerland) · 2020Article
- Enhancing innate immunity against virus in times of COVID-19: Trying to untangle facts from fictions.The World Allergy Organization journal · 2020Review
- Differential Th Cell-Related Immune Responses in Young Physically Active Men after an Endurance Effort.Journal of clinical medicine · 2020Article
- Moderate- to high intensity aerobic and resistance exercise reduces peripheral blood regulatory cell populations in older adults with rheumatoid arthritis.Immunity & ageing : I & A · 2020Article
- Changes in Lymphocyte Composition and Functionality After Intensive Training and Exhausting Exercise in Rats.Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeT-regulatory cells (Tregs) are a sub-population of lymphocytes that act to suppress aberrant immune responses. We investigated changes in the numbers of naïve and terminally differentiated Tregs in the peripheral blood to establish their role in the immuno-suppressive response to prolonged exercise.
methodsBlood was drawn from seventeen experienced runners (age 40 ± 12 years; height 1.75 ± 0.08 m; mass 71.4 ± 10.8 kg) before, ~1 h after (POST-1h), and on the day following the marathon (POST-1d). Tregs (CD3
resultsThe absolute number of Tregs decreased (27%) POST-1h marathon (P < 0.001) but increased (21%) at POST-1d (P < 0.01). Naïve CD45RA
conclusionsThese results suggest that Tregs do not play a major role in immune suppression in the early hours of recovery from a marathon. However, terminally differentiated HLA-DR
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.