Evidence map›Paper›PMID 28646241›Full record

ArticleBrain structure & function2017

Never forget a name: white matter connectivity predicts person memory.

Athanasia Metoki, Kylie H Alm, Yin Wang, Chi T Ngo, Ingrid R Olson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain structure & function, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Evidence for the role of affective theory of mind in face-name associative memory.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2024
    Article
  9. Article
  10. The fornix supports episodic memory during childhood.Cerebral cortex (New York, N.Y. : 1991) · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. White matter pathways and social cognition.Neuroscience and biobehavioral reviews · 2018
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Athanasia MetokiDepartment of Psychology, Temple University, Weiss Hall, 1701 N. 13th Street, Philadelphia, PA, 19122, USA. athanasia.metoki@temple.edu.ORCID http://orcid.org/0000-0002-8945-269X
Kylie H AlmDepartment of Psychology, Temple University, Weiss Hall, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Yin WangDepartment of Psychology, Temple University, Weiss Hall, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Chi T NgoDepartment of Psychology, Temple University, Weiss Hall, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Ingrid R OlsonDepartment of Psychology, Temple University, Weiss Hall, 1701 N. 13th Street, Philadelphia, PA, 19122, USA. iolson@temple.edu.

Funding

Research Training in Age-Related Cognitive DisordersT32AG027668 · NIA · JOHNS HOPKINS UNIVERSITY · PI MARILYN S. ALBERT · 2007 to 2026
$6.3M
The Neural Basis of Social KnowledgeR01MH091113 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI OLSON, INGRID R · 2010 to 2019
$3.7M
National Institutes of Health RO1 MH091113NIA NIH HHS T32 AG027668NIMH NIH HHS R01 MH091113
6 · The paper itself

Abstract

Through learning and practice, we can acquire numerous skills, ranging from the simple (whistling) to the complex (memorizing operettas in a foreign language). It has been proposed that complex learning requires a network of brain regions that interact with one another via white matter pathways. One candidate white matter pathway, the uncinate fasciculus (UF), has exhibited mixed results for this hypothesis: some studies have shown UF involvement across a range of memory tasks, while other studies report null results. Here, we tested the hypothesis that the UF supports associative memory processes and that this tract can be parcellated into sub-tracts that support specific types of memory. Healthy young adults performed behavioral tasks (two face-name learning tasks, one word pair memory task) and underwent a diffusion-weighted imaging scan. Our results revealed that variation in UF microstructure was significantly associated with individual differences in performance on both face-name tasks, as well as the word association memory task. A UF sub-tract, functionally defined by its connectivity between face-selective regions in the anterior temporal lobe and orbitofrontal cortex, selectively predicted face-name learning. In contrast, connectivity between the fusiform face patch and both anterior face patches had no predictive validity. These findings suggest that there is a robust and replicable relationship between the UF and associative learning and memory. Moreover, this large white matter pathway can be subdivided to reveal discrete functional profiles.

Indexed as

Brain MappingNamesAdolescentAdultAnalysis of VarianceAnisotropyAssociation LearningDiffusion Tensor ImagingFaceFemaleHumansImage Processing, Computer-AssistedMaleMemoryNeural PathwaysPhotic StimulationAnterior temporal lobeAssociative memoryDiffusion imagingFacesOrbitofrontal cortexUncinate fasciculusWhite matter

Identifiers

PMID28646241
PMCPMC5884066

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.