ArticleDrug metabolism and disposition: the biological fate of chemicals2017
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Article in Drug metabolism and disposition: the biological fate of chemicals, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Proteomic and functional profiling of suspended jejunal enteroids reveals pharmacokinetic fidelity to native intestine.iScience · 2026Article
- The 2R, 3R isomer of 2, 3-butanediol prevents weight gain and decreases plasma glucose concentration of mice fed a fat-enriched diet.Frontiers in physiology · 2026Article
- Bacterial exopolysaccharides mediate activation of flavin-containing monooxygenase 2 to extend lifespan in Caenorhabditis elegans.Cell communication and signaling : CCS · 2025Article
- Clinical and metabolic phenotypes of Oxford Biobank subjects with variations in human flavin-containing monooxygenase 5 (FMO5).Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Gene-by-environment Interactions and Adaptive Body Size Variation in Mice From the Americas.Molecular biology and evolution · 2025Article
- Taurine and proline promote lung tumour growth by co-regulating Azgp1/mTOR signalling pathway.NPJ precision oncology · 2025Article
- Role of NAD metabolism-related genes in diabetic nephropathy: subtype classification, biomarker identification, and association with renal function.Experimental biology and medicine (Maywood, N.J.) · 2025Article
- A Sex-specific Role for Goblet Cells and Mucus Homeostasis in the Intestine.Cellular and molecular gastroenterology and hepatology · 2025Article
- Epithelial NSD2 maintains FMO-mediated taurine biosynthesis to prevent intestinal barrier disruption.Clinical and translational medicine · 2024Article
- Flavin-containing monooxygenase (FMO): Beyond xenobiotics.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024Review
- Puerarin ameliorates non-alcoholic fatty liver disease by inhibiting lipid metabolism through FMO5.Frontiers in pharmacology · 2024Article
- Article
- Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker ofFrontiers in physiology · 2022Article
- Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators.Antioxidants (Basel, Switzerland) · 2021Article
- Association of grandmaternal smoking during pregnancy with DNA methylation of grandchildren: the Isle of Wight study.Epigenomics · 2021Article
- NHR-49/PPAR-α and HLH-30/TFEB cooperate foreLife · 2021Article
- Metabolomics Signatures of Aging: Recent Advances.Aging and disease · 2021Review
- Alcoholic fatty liver disease inhibited the co-expression of Fmo5 and PPARα to activate the NF-κB signaling pathway, thereby reducing liver injury via inducing gut microbiota disturbance.Journal of experimental & clinical cancer research : CR · 2021Article
- Flavin-Containing Monooxygenases Are Conserved Regulators of Stress Resistance and Metabolism.Frontiers in cell and developmental biology · 2021Article
- Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.Nature structural & molecular biology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
We have previously identified flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic aging. The aim of the present study was to investigate the role of FMO5 in glucose homeostasis and the impact of diet and gut flora on the phenotype of mice in which the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.