Evidence map›Paper›PMID 28645971›Full record

ArticleBMJ open2017

Association between chronic obstructive pulmonary disease and increased risk of benign prostatic hyperplasia: a retrospective nationwide cohort study.

Yi-Hao Peng, Chien-Wen Huang, Wei-Chih Liao, Hsuan-Ju Chen, Ming-Chien Yin, Yu-Ming Huang, Trong-Neng Wu, Wen-Chao Ho

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. A RareBalkan medical journal · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yi-Hao PengDepartment of Public Health, China Medical University, Taichung, Taiwan.
Chien-Wen HuangDivision of Chest Medicine, Department of Internal Medicine, Asia University Hospital, Taichung, Taiwan.
Wei-Chih LiaoDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Hsuan-Ju ChenCollege of Medicine, China Medical University, Taichung, Taiwan.
Ming-Chien YinDepartment of Public Health, China Medical University, Taichung, Taiwan.
Yu-Ming HuangDivision of Respiratory Therapy, Asia University Hospital, Asia University, Taichung, Taiwan.
Trong-Neng WuDepartment of Health Care Administration, Asia University, Taichung, Taiwan.
Wen-Chao HoDepartment of Public Health, China Medical University, Taichung, Taiwan.
Asia University · TWChina Medical University Hospital · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic obstructive pulmonary disease (COPD) and benign prostatic hyperplasia (BPH) are common disorders in ageing male populations. Nevertheless, the relationship between the two diseases has rarely been explored. The objective of this study was to examine whether patients with COPD are at an increased risk of BPH.

designRetrospective nationwide cohort study.

settingData retrieved from the Taiwan National Health Insurance Research Database.

participantsOverall, 19 959 male patients aged 40 years and over with newly diagnosed COPD between 2000 and 2006 were included as the COPD group, and 19 959 sex-matched and age-matched enrollees without COPD were included as the non-COPD group. Both groups were followed-up until the end of 2011. OUTCOME MEASURES: A Cox proportional hazards regression model was used to compute the risk of BPH in patients with COPD compared with enrollees without COPD.

resultsThe overall incidence rate of BPH was 1.53 times higher in the COPD group than that in the non-COPD group (44.7 vs 25.7 per 1000 person-years, 95% CI 1.46 to 1.60) after adjusting for covariates. An additional stratified analysis revealed that this increased risk of BPH in patients with COPD remained significantly higher than that in enrollees without COPD in all men aged 40 years and over.

conclusionAfter adjustment for covariates, male patients with COPD were found to be at a higher risk of BPH. We suggest that clinicians should be cautious about the increased risk of BPH in male patients with COPD.

Indexed as

AdultAgedDatabases, FactualHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProstatic HyperplasiaPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsTaiwanbenign prostatic hyperplasiachronic obstructive pulmonary diseasecohort studycomorbiditylower urinary tract symptoms.

Identifiers

PMID28645971
PMCPMC5734354
OpenAlexW2653561775

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.