Evidence map›Paper›PMID 28645916›Full record

ArticleThe EMBO journal2017

Structures and dynamics of hibernating ribosomes from

Iskander Khusainov, Quentin Vicens, Rustam Ayupov, Konstantin Usachev, Alexander Myasnikov, Angelita Simonetti, Shamil Validov, Bruno Kieffer, Gulnara Yusupova, Marat Yusupov and 1 more

Abstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Article
  3. Structural insights into RNA recognition by theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Discovery of Ribosomal Protein bL31 fromInternational journal of molecular sciences · 2023
    Review
  18. Article
  19. Using deep-learning predictions of inter-residue distances for model validation.Acta crystallographica. Section D, Structural biology · 2022
    Article
  20. Bidirectional sequestration between a bacterial hibernation factor and a glutamate metabolizing protein.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Iskander KhusainovDépartement de Biologie et de Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR7104, INSERM U964, Université de Strasbourg, Illkirch, France.
Quentin VicensCNRS, Architecture et Réactivité de l'ARN, UPR 9002, Université de Strasbourg, Strasbourg, France.ORCID 0000-0003-3751-530X
Rustam AyupovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.ORCID 0000-0002-6769-7194
Konstantin UsachevInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.ORCID 0000-0002-6331-7764
Alexander MyasnikovDépartement de Biologie et de Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR7104, INSERM U964, Université de Strasbourg, Illkirch, France.
Angelita SimonettiCNRS, Architecture et Réactivité de l'ARN, UPR 9002, Université de Strasbourg, Strasbourg, France.
Shamil ValidovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Bruno KiefferDépartement de Biologie et de Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR7104, INSERM U964, Université de Strasbourg, Illkirch, France.
Gulnara YusupovaDépartement de Biologie et de Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR7104, INSERM U964, Université de Strasbourg, Illkirch, France.
Marat YusupovDépartement de Biologie et de Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR7104, INSERM U964, Université de Strasbourg, Illkirch, France marat@igbmc.fr y.hashem@ibmc-cnrs.unistra.fr.
Yaser HashemCNRS, Architecture et Réactivité de l'ARN, UPR 9002, Université de Strasbourg, Strasbourg, France marat@igbmc.fr y.hashem@ibmc-cnrs.unistra.fr.ORCID 0000-0003-4264-5918
Centre National de la Recherche Scientifique · FRKazan Federal University · RU

Funding

European Research Council 294312
6 · The paper itself

Abstract

In bacteria, ribosomal hibernation shuts down translation as a response to stress, through reversible binding of stress-induced proteins to ribosomes. This process typically involves the formation of 100S ribosome dimers. Here, we present the structures of hibernating ribosomes from human pathogen

Indexed as

DimerizationBacterial ProteinsCryoelectron MicroscopyMagnetic Resonance SpectroscopyModels, MolecularProtein BindingProtein Interaction MappingRibosomesRNA, Ribosomal, 16SStaphylococcus aureusBacterial ProteinsRNA, Ribosomal, 16Scryo‐electron microscopyhibernationpathogenribosome

Identifiers

PMID28645916
PMCPMC5510003
OpenAlexW2683537437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.