GuidelineChest2017
Etiologies of Chronic Cough in Pediatric Cohorts: CHEST Guideline and Expert Panel Report.
Guideline in Chest, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Coughing children in family practice and primary care: a systematic review of prevalence, aetiology and prognosis.BMC pediatrics · 2021Pooled it
- Chronic Cough and Gastroesophageal Reflux in Children: CHEST Guideline and Expert Panel Report.Chest · 2019Guideline
- Article
- Etiologies of chronic cough in children: a two-year experience from a tertiary pediatric pulmonology center.Turkish journal of medical sciences · 2026Article
- [Chronic cough and otorhinolaryngology in children].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Review
- Cough in Protracted Bacterial Bronchitis and Bronchiectasis.Journal of clinical medicine · 2024Article
- Controversies in Antibiotic Use for Chronic Wet Cough in Children.The Journal of pediatrics · 2024Article
- Factors influencing behavioral cough suppression therapy in children with nonspecific chronic cough.Pediatric pulmonology · 2023Observational
- Increased serum eosinophilic cationic protein in children with nonspecific chronic cough.Clinical and experimental pediatrics · 2023Article
- Cough Hypersensitivity Syndrome: Why Its Use Is Inappropriate in Children.Journal of clinical medicine · 2023Article
- Review
- Pepsin and the Lung-Exploring the Relationship between Micro-Aspiration and Respiratory Manifestations of Gastroesophageal Reflux Disease.Journal of personalized medicine · 2022Review
- Cough hypersensitivity and chronic cough.Nature reviews. Disease primers · 2022Review
- A multi-disciplinary approach to chronic cough in children.Laryngoscope investigative otolaryngology · 2022Review
- Diagnostic Accuracy of Nasopharyngeal Swab Cultures in Children Less Than Five Years with Chronic Wet Cough.Children (Basel, Switzerland) · 2021Article
- Predictors of the Development of Protracted Bacterial Bronchitis following Presentation to Healthcare for an Acute Respiratory Illness with Cough: Analysis of Three Cohort Studies.Journal of clinical medicine · 2021Article
- WAO-ARIA consensus on chronic cough - Part II: Phenotypes and mechanisms of abnormal cough presentation -The World Allergy Organization journal · 2021Review
- Review
- Positive bronchoalveolar lavage pepsin assay associated with viral and fungal respiratory infections in children with chronic cough.Pediatric pulmonology · 2021Article
- [Value of airway pH monitoring in determining the association between chronic cough and laryngopharyngeal reflux in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 8 institutions in 3 countries.
Funding
Abstract
backgroundThere is no published systematic review on the etiologies of chronic cough or the relationship between OSA and chronic cough in children aged ≤ 14 years. We thus undertook a systematic review based on key questions (KQs) using the Population, Intervention, Comparison, Outcome format. The KQs follow: Among children with chronic (> 4 weeks) cough (KQ 1) are the common etiologies different from those in adults? (KQ 2) Are the common etiologies age or setting dependent, or both? (KQ 3) Is OSA a cause of chronic cough in children?
methodsWe used the CHEST Expert Cough Panel's protocol and the American College of Chest Physicians (CHEST) methodological guidelines and Grading of Recommendations Assessment, Development, and Evaluation framework. Data from the systematic reviews in conjunction with patients' values and preferences and the clinical context were used to form recommendations. Delphi methodology was used to obtain consensus.
resultsCombining KQs 1 and 2, we found moderate-level evidence from 10 prospective studies that the etiologies of cough in children are different from those in adults and are setting dependent. Data from three studies found that common etiologies of cough in young children were different from those in older children. However, data relating sleep abnormalities to chronic cough in children were found only in case studies.
conclusionsThere is moderate-quality evidence that common etiologies of chronic cough in children are different from those in adults and are dependent on age and setting. As there are few data relating OSA and chronic cough in children, the panel suggested that these children should be managed in accordance with pediatric sleep guidelines.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.