ArticleDrug and alcohol dependence2017
The neurochemical consequences of methamphetamine self-administration in male and female rats.
Article in Drug and alcohol dependence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 27 citations in OpenAlex.
- Differences between males and females in psychostimulant/sucrose self-administration (when observed) may not necessarily be driven by biological sex.bioRxiv : the preprint server for biology · 2026Article
- Article
- Sex-specific effects of predator scent stress on fear, anxiety-like behavior and methamphetamine seeking in rats.Addiction neuroscience · 2025Article
- Methamphetamine produces behavioral flexibility deficits that are attenuated by COX-2 inhibition in both male and female rats.Addiction neuroscience · 2025Article
- Methamphetamine self-administration causes neuronal dysfunction in rat medial prefrontal cortex in a sex-specific and withdrawal time-dependent manner.Frontiers in pharmacology · 2025Article
- The estrous cycle has no effect on incubation of methamphetamine craving and associated Fos expression in dorsomedial striatum and anterior intralaminar nucleus of thalamus.Addiction neuroscience · 2024Article
- Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice.International journal of molecular sciences · 2024Article
- Sex differences in nicotine intake and relapse behavior in nicotine-dependent adult wistar rats.Frontiers in pharmacology · 2024Article
- Modeling methamphetamine use disorder in mammals: Sex differences in behavioral, biochemical, and transcriptional consequences.Advances in pharmacology (San Diego, Calif.) · 2024Article
- Interaction of Brain-Derived Neurotrophic Factor with the Effects of Chronic Methamphetamine on Prepulse Inhibition in Mice Is Independent of Dopamine D3 Receptors.Biomedicines · 2023Article
- Repeated methamphetamine exposure decreases plasma brain-derived neurotrophic factor levels in rhesus monkeys.General psychiatry · 2023Article
- Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts.Neuroscience and biobehavioral reviews · 2022Review
- Sex Differences in Psychostimulant Abuse: Implications for Estrogen Receptors and Histone Deacetylases.Genes · 2022Review
- Sex-Specific Alterations in Dopamine Metabolism in the Brain after Methamphetamine Self-Administration.International journal of molecular sciences · 2022Article
- Sex- and Brain Region-specific Changes in Gene Expression in Male and Female Rats as Consequences of Methamphetamine Self-administration and Abstinence.Neuroscience · 2021Article
- The emergence of cardiac changes following the self-administration of methamphetamine.Drug and alcohol dependence · 2020Article
- Neurochemical and behavioral comparisons of contingent and non-contingent methamphetamine exposure following binge or yoked long-access self-administration paradigms.Psychopharmacology · 2020Article
- Synthetic cathinone self-administration in female rats modulates neurotransmitter levels in addiction-related brain regions.Behavioural brain research · 2019Article
- Interaction of stress and stimulants in female rats: Role of chronic stress on later reactivity to methamphetamine.Behavioural brain research · 2019Article
- Sex Differences in Escalated Methamphetamine Self-Administration and Altered Gene Expression Associated With Incubation of Methamphetamine Seeking.The international journal of neuropsychopharmacology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMethamphetamine (METH) is an addictive substance that is used in both males and females. Few preclinical studies have focused on understanding sex-differences in the neurochemical consequences of contingent METH. The purpose of the current study was to investigate potential sex-differences in the neurochemical consequences of METH self-administration.
methodsMale and female adult rats were given extended access to METH or saline self-administration for 7d. Following self-administration, hippocampal brain-derived neurotrophic factor (BDNF) and striatal dopamine transporter (DAT) were assessed via western blotting.
resultsMale and female rats had similar METH intake. METH self-administration reduced striatal DAT in both sexes, but only males that self-administered METH had elevated hippocampal BDNF levels.
conclusionsSex-differences exist in the neurochemical consequences of METH self-administration. These differences may lead to sex-specific vulnerability to the toxic effects of METH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.