ArticleNature chemistry2017
A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF
Article in Nature chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 155 citations in OpenAlex.
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- One Single Tube Reaction of Aptasensor-Based Magnetic Sensing System for Selective Fluorescent Detection of VEGF in Plasma.Biosensors · 2023Article
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- Advanced bioactive nanomaterials for biomedical applications.Exploration (Beijing, China) · 2021Review
- Engineered polymer nanoparticles incorporating l-amino acid groups as affinity reagents for fibrinogen.Journal of pharmaceutical analysis · 2021Article
- Synthetic hydrogel nanoparticles for sepsis therapy.Nature communications · 2021Article
- Molecular configuration-mediated thermo-responsiveness in oligo(ethylene glycol) derivatives attached on gold nanoparticles.Nanoscale advances · 2021Article
- Protein Denaturation Through the Use of Magnetic Molecularly Imprinted Polymer Nanoparticles.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein affinity reagents are widely used in basic research, diagnostics and separations and for clinical applications, the most common of which are antibodies. However, they often suffer from high cost, and difficulties in their development, production and storage. Here we show that a synthetic polymer nanoparticle (NP) can be engineered to have many of the functions of a protein affinity reagent. Polymer NPs with nM affinity to a key vascular endothelial growth factor (VEGF
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.