Evidence map›Paper›PMID 28644055›Full record

ArticleChannels (Austin, Tex.)2017

Regulation of transient receptor potential melastatin 4 channel by sarcoplasmic reticulum inositol trisphosphate receptors: Role in human detrusor smooth muscle function.

Aaron Provence, Eric S Rovner, Georgi V Petkov

Open access · goldAbstract read
In one paragraph

Article in Channels (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Aaron Provencea Department of Drug Discovery and Biomedical Sciences , South Carolina College of Pharmacy, University of South Carolina , Columbia , SC , USA.
Eric S Rovnerb Department of Urology , Medical University of South Carolina , Charleston , SC , USA.
Georgi V Petkova Department of Drug Discovery and Biomedical Sciences , South Carolina College of Pharmacy, University of South Carolina , Columbia , SC , USA.
Medical University of South Carolina · USUniversity of South Carolina · US

Funding

Role of TRP channels in human detrusor function and dysfunctionR01DK106964 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI XIN, WENKUAN · 2015 to 2019
$1.7M
KCNQ Channels of the Urinary Bladder: A Functional Role and Therapeutic PotentialF31DK104528 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PROVENCE, AARON · 2014 to 2017
$95k
NIDDK NIH HHS F31 DK104528NIDDK NIH HHS R01 DK106964
6 · The paper itself

Abstract

We recently reported key physiologic roles for Ca

Indexed as

AgedAnimalsFemaleHumansInositol 1,4,5-Trisphosphate ReceptorsMaleMiddle AgedMuscle, SmoothMyocytes, Smooth MuscleSarcoplasmic ReticulumSignal TransductionTRPM Cation ChannelsUrinary BladderInositol 1,4,5-Trisphosphate ReceptorsTRPM4 protein, humanTRPM Cation Channelspatch-clampproximity ligation assayTRPM4 channelxestospongin-C

Identifiers

PMID28644055
PMCPMC5626371
OpenAlexW2689780002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.